利用高碘酸钠/NaIO4氧化裂解碳碳键生成两个醛的反应,称为Lemieux-Johnson氧化。1956年,Lemieux和Johnson首先报道了此反应【Pappo, R.; Allen, D. S.; Lemieux, R. U. and Johnson, W. S., J. Org. Chem., 1956, 21, 478】。OsO4/NaIO4被称为Lemieux-Johnson试剂...
The Lemieux–Johnson oxidation was employed for the cleavage of the carbon–carbon double bond of shikimic acid derivatives. Through this procedure, a series of the sixteen novel (2S,3S,4R)-2,3,4,7-tetrahydroxy-6-oxoheptanals bearing three contiguous stereocentres have been synthesized in ...
Lemieux-Johnson氧化反应 利用高碘酸钠/NaIO4氧化裂解碳碳键生成两个醛的反应,称为Lemieux-Johnson氧化。1956年,Lemieux和Johnson首先报道了此反应【Pappo, R.; Allen, D. S.; Lemieux, R. U. and Johnson, W. S.,J. Org. Chem.,1956, 21, 478】。OsO4/NaIO4被称为Lemieux-Johnson试剂,此反应也被称...
The Lemieux-Johnson oxidation is the oxidative cleavage of alkenes to aldehydes using a catalytic amount of osmium tetroxide or ruthenium tetroxide and a stoichiometric amount of alkali metal periodate. It serves as an alternative to ozonolysis. The reaction was first reported by Raymond U. Lemieux ...
OsO4/NaIO4被称为Lemieux-Johnson试剂,此反应也被称为Lemieux-Johnson氧化。与臭氧化法相比,OsO4/NaIO4是一种温和的烯烃氧化开裂法,在天然产物合成中很有用。烯烃先与OsO4反应生成锇酸酯,再用过碘酸钠氧化,发生开裂,在生成羰基化合物的同时,OsO4再生,所以OsO4用催化量即可。...
Shikimic acidLemieux-Jonson oxidation6-oxoheptanalsThe Lemieux–Johnson oxidation was employed for the cleavage of the carbon–carbon double bond of shikimic acid derivatives. Through this procedure, a series of the sixteen novel (2 S,3 S,4 R)-2,3,4,7-t...Miroslav Psotka...
The Lemieux-Johnson oxidation was employed for the cleavage of the carbon-carbon double bond of shikimic acid derivatives. Through this procedure, a series of the sixteen novel (2S,3S,4R)-2,3,4,7-tetrahydroxy-6-oxoheptanals bearing three contiguous stereocentres have been synthesized in ...
Functionalized-1,3,4-oxadiazole ligands for the ruthenium-catalyzed Lemieux-Johnson type oxidation of olefins and alkynes in waterShaima Hkiri a bSoufiane Touil bAli Samarat bDavid Sémeril a
The article shares an ownership lesson for former Los Angeles Lakers basketball star Magic Johnson, who led the Guggenheim group in its acquisition of the bankrupt Los Angeles Dodgers baseball team, citing the success stories of sports stars Michael Jordan, Mario Lemieux and Nolan Ryan. The three...
OsO4/NaIO4被称为Lemieux-Johnson试剂,此反应也被称为Lemieux-Johnson氧化。与臭氧化法相比,OsO4/NaIO4是一种温和的烯烃氧化开裂法,在天然产物合成中很有用。烯烃先与OsO4反应生成锇酸酯,再用过碘酸钠氧化,发生开裂,在生成羰基化合物的同时,OsO4再生,所以OsO4用催化量即可。当生成的醛易于分子内缩合时,反应最...