Leishmaniasis is an uncommon infectious disease in the UK with a variety of clinical presentations. Physicians should remember to consider this diagnosis in patients with an appropriate travel history (including the Mediterranean basin) and seek help with diagnostics from a specialised parasitology ...
King’s College London, London, UK D. T. Hart Copyright information © 1989 Springer Science+Business Media New York About this chapter Cite this chapter Kiderlen, A.F., Lohmann-Matthes, ML. (1989). Treatment of Experimental Cutaneous and Visceral Murine Leishmaniasis with Recombinant Gamma-...
Cutaneous Leishmaniasis: Current Treatment Practices in the USA for Returning Travelers Leishmaniasis, a protozoal infection transmitted by sandfly bite, produces a clinical spectrum of disease ranging from asymptomatic infection to ulcerative... DP Eiras,LA Kirkman,HW Murray - 《Current Treatment Option...
The availability of polymerase chain reaction assays amplifying leishmanial genetic material has been a major step forward in improving the diagnosis of leishmanial disease and the response to treatment. 展开 关键词: anti-leishmanial antibodies cutaneous leishmaniasis Europe leishmania PCR parasitological ...
Currently, treatment regimens for visceral leishmaniasis (VL) are limited because of the presence of numerous adverse effects. Nicotinamide, a readily available and cost-effective vitamin, has been widely acknowledged for its safety profile. Several stud
Although this class of drugs has been used for over 60 years for leishmaniasis treatment, it is only in the past 2 years that the mechanisms of action and resistance have been identified, related to drug metabolism, thiol metabolism, and drug efflux. With the introduction of new therapies, ...
Although these drugs are currently being abandoned as first-line treatment in the Indian subcontinent, we can still draw many lessons from the experience with antimonials with respect to (1) speculation of the future of the few additional available drugs and (2) the design and implementation of...
Objective:We report a rare UK case of laryngeal leishmaniasis, mimicking laryngeal candidiasis, associated with long term steroid inhaler use.Methods:Case report and review of the world literature concerning leishmaniasis.Results:Laryngeal leishmaniasis is a protozoal infection which is rare in the West...
The armamentarium of antileishmanial treatment is small; it includes pentavalent antimonials, amphotericin B deoxycholate and its lipid formulation, paromomycin, miltefosine, azoles, and pentamidine. For several decades, pentavalent antimonials (Sbv) were the standard first-line drug against leishmaniasis...
This intervention was in form of rodent control and hygiene or waste management and through the free treatment and care of leishmaniasis cases. The oasean ecosystems are located in the southern provinces of Morocco. These provinces constitute the Pre-Sahara region. The oasis is a wet zone in ...