Factor V Leiden deficiency?autoimmune disorderscoeliac diseasetype 1 diabetesPubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites....
(redirected fromFactor V Leiden mutation) Thesaurus Medical Legal Acronyms Encyclopedia mu·ta·tion (myo͞o-tā′shən) n. 1.The act or process of being altered or changed. 2.An alteration or change, as in nature, form, or quality. ...
Individuals with a positive screening assay should have the DNA test for confirmation and to distinguish heterozygotes, homozygotes, and "pseudohomozygotes" who are heterozygous for both Factor V Leiden and a second mutation causing Factor V deficiency. When relatives of individuals known to have ...
We investigated the presence of the gene mutation of factor V, FV ^l)6Q or factor V Leiden, responsible for activated protein C resis- nce, in DNA samples of 127 probands and 188 relatives from 128 jinhes with antithrombin deficiency.The factor V mutationwas iden- ned in 18 families. Ni...
The prevalence of factor V Leiden, prothrombin G20210A and methylenetetrahydrofolate reductase polymorphism C677T among G6PD deficient individuals from Wes... It has been suggested that the allele frequency of thrombophilic mutations is affected by glucose-6-phosphate dehydrogenase ( G6PD ) deficiency....
Role of factor V Leiden or G20210A prothrombin mutation in patients with symptomatic pulmonary embolism and deep vein thrombosis: a meta-analysis of the literature. J Thromb Haemost, 2012, 10(4): 732-737. 19 Ali N, Ayyub M. High prevalence of protein C, protein S, antithrombin deficiency...
Leiden (FV R506Q) in families with inherited antithrombin deficiency. Thromb Haemost 1996; 75: 417–421. Article CAS Google Scholar Koeleman BPC, Reitsma PH, Allaart CF, Bertina RM . Activated protein C resistance as an additional risk factor for thrombosis in protein C-deficient families. ...
The relationship of the factor V Leiden mutation and pregnancy outcomes for mother and fetus. OBJECTIVE: We sought to estimate the frequency of pregnancy-related thromboembolic events among carriers of the factor V Leiden (FVL) mutation without a pe... D Dizon-Townson,C Miller,B Sibai,... ...
Factor V Leiden mutation is a common genetic risk factor for venous thrombosis. It has been documented in up to 65% of patients with unexplained venous thromboembolism. This genetic mutation is now known to be the most common inherited cause of activated protein C (APC) resistance. Recently, ...
OBJECTIVE: We sought to estimate the frequency of pregnancy-related thromboembolic events among carriers of the factor V Leiden (FVL) mutation without a personal history of thromboembolism, and to evaluate the impact of maternal and fetal FVL mutation carriage or other thrombophilias on the risk of...