Purpose The aim of this study was to determine the risk of major adverse cardiovascular events (MACE) during follow-up in post myocardial infarction (PMI) patients according to the achievement of the guidelines-recommended goals in terms of LDL-C reduction. Methods We conducted a retrospective ...
This concept led to a substantial reduction of the LDL-C goals recommended by the most recent guidelines for the management of dyslipidemias (Mach et al. 2020). Statins, which represent the cornerstone for the treatment of hypercholesterolemia, have shown approximately a 20% reduction in the ...
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After 14 weeks of simvastatin (20-80 mg) treatment, approximately 90% of the patients achieved LDL-C goals according to US (87%) and European (94%) guidelines. Most patients (72-93%) achieved target LDL-C levels on 20 mg simvastatin. An estimated 14% of the patients required titration...
9,10,11This direct assay meets the 1995 NCEP goals of < 4 % total CV, bias ≤ 4 %versus reference method, and ≤ 12 % total analytical error. 12Test principleHomogeneous enzymatic colorimetric assay.DetergentLDL-cholesterol esters+ H 2 OCholesterol esteraseCholesterol + free fattyacids (...
the disease and the need to manage LDL-C. Many patients also do not have a clear understanding of their treatment goals. They expect their healthcare providers to come up with an appropriate treatment strategy when they visit the doctor, and they often do not take their prescribed medications...
Current guidelines recommend initiating statin therapy in patients with a yearly ... R Bulbulia,J Armitage - 《Current Opinion in Lipidology》 被引量: 0发表: 2012年 LDL Cholesterol Goals in High-Risk Patients: How Low Do We Go and How Do We Get There? It is widely recognised that low-...
The objective of the present study was to investigate the prevalence of elevated Lp(a) levels in a population of patients with CAD and how they impact LDL-C concentrations and the achievement of the LDL-C goals set forth in the guidelines for very high-risk CAD patients. ...
Attainment of treatment goals was defined according to 2016 ESC guidelines for the management of dyslipidemia: LDL-C < 70 mg/dl and HbA1c < 7.0%.2 An LDL-C treatment goal of <55 mg/dl according to ...
On the basis of this clinical trial evidence, progressively lower LDL-C goals for increasing numbers of patients, stratified by absolute CVD risk, have been recommended in guidelines for cholesterol management and CVD prevention. Some notable exceptions have been made, however, such as patients with...