High-density lipoprotein (HDL): This is often referred to as "good" cholesterol as it absorbs excess cholesterol in the blood and carries it back to the liver to be flushed from the body. As a general rule, you want more HDL to lower your risk for heart disease and stroke. The combina...
PURPOSE. To compare high- or very high-risk male and female patients regarding contemporary 1-year low-density lipoprotein cholesterol (LDL-C) goal attainment, lipid-lowering therapy (LLT) intensity, and major adverse cardiovascular event (MACE) rate. METHODS. SANTORINI is an observational, ...
(LLT) goals, a sex-focused assessment is essential and more studies are needed to bring new evidence to clinicians. This study aims to assess the role of sex in attaining low-density lipoprotein cholesterol (LDL-C) goals, after correction for age, CV risk category, LLT intensity, and ...
Age. Cholesterol tends to get higher over time. That’s because the body has a harder time clearing out cholesterol as you get older. Sex. Women and people assigned female at birth might see their LDL levels go up after menopause.
We found that oxidized low-density lipoprotein (ox-LDL) cholesterol significantly up-regulates both the expression of miRNA-223 and L-type calcium channel protein. In contrast, knockdown of miRNA-223 reduced L-type calcium channel protein expression, while genetic knockdown of endogenous miRNA-223 ...
As we learned above, some cholesterol proteins are heart healthy while others are not. Which means it’s possible to have unhealthy levels of “bad” cholesterol even if your total cholesterol is in the target range. High non-HDL cholesterol is generally considered a bigger risk factor for ...
Structure of an LDL-particle. The core of the particle (yellow) contains cholesterol and triglycerides. The blue and white molecule is apolipoprotein B (ApoB). Every LDL particle contains one molecule of ApoB. Lipoproteins are biochemical structures that enable the transport of lipids such as cho...
HDL-Cholesterol Subfractions in Healthy Males: Relation to Serum Triglyceride Levels and Age The relationship between plasma HDL-cholesterol subfractions (HDL2 and HDL3), measured using a differential precipitation method, and serum triglycerides, was studied in 402 healthy Caucasian males attending a ...
Potential participants (21 to 75 y of age) were recruited from the Chicago metropolitan area and prescreened by telephone. Eligibility was further assessed at screening and baseline visits (wk –6, –5, –1 and 0). Subjects had to have LDL cholesterol between 3.36 and 5.17 mmol/L, triglyce...
Similar to cholesterol, plant sterols are susceptible to oxidation. However, less is known about the potential atherogenicity of oxidised plant sterols (oxyphytosterols). In the present study, the atherogenicity of a mixture of oxyphytosterols was examined by feeding female LDL receptor-deficient (...