LDL cholesterollipid lowering agentsstatinsLowering LDL cholesterol in patients has been directly linked to lowering the incidence of cardiovascular disease and represents one of the most successful avenues of medicinal chemistry. This chapter discusses current drugs on the market and in development that ...
(total cholesterol,TC),低密度脂蛋白(low density lipoprotein in cholesterol, LDL) 升高,高密度脂蛋白(high density lipoprotein in cholesterol, HDL) 降低与心... Y.,Meguro,and,... - 《Atherosclerosis Supplements》 被引量: 115发表: 2011年 Vitamins C and E prevent endothelial VEGF and VEGFR-2 ov...
2022年:Association of low-density lipoprotein cholesterol levels with the risk of mortality and cardiovascular events: A meta-analysis of cohort studies with 1,232,694 participants(低密度脂蛋白胆固醇水平与死亡和心血管事件风险的关联:对1,232,694 名参与者进行的队列...
Experimental atherosclerosis in rabbits fed cholesterol-free diets. 2. Influence of various carbohydrates It has been shown that the addition of saturated fat to a semi-synthetic, cholesterol-free ration is atherogenic for rabbits. Experiments were carried out ... D Kritchevsky,P Sallata,SA Tepper...
(2005) Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease. N Engl J Med 352: 29–38 Intensive statin therapy has been shown to be more effective than moderate therapy in reducing the progression of atherosclerosis and improving clinical outcomes in patients with ...
[1]2023 Update on European Atherosclerosis Society Consensus Statement on Homozygous Familial Hypercholesterolaemia: new treatments and clinical guidance. European Heart Journal, 02 May 2023 声明:本文仅供医疗卫生专业人士了解最新医药资讯参考使用,不代表本平台观点。该信息不能以任何方式取代专业的医疗指导,也不...
Decreasing low-density lipoprotein cholesterol (LDL-C) is one of the few established and proven principles for the prevention and treatment of atherosclerosis. The higher the individual cardiovascular risk, the higher the benefit of lipid-lowering pharmacotherapy. Therefore, treatment options are chosen ...
[25]Ray KK, et al. Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol. N Engl J Med. 2020 Apr 16;382(16):1507-1519. [26]霍勇, 李勇, 韩雅君, 等. Inclisiran在中国大陆ASCVD或ASCVD高危受试者...
LDL cholesterol: Bad cholesterol, or bad science? The belief that low-density lipoprotein (LDL) cholesterol causes atherosclerosis and subsequent heart disease is a fundamental precept of modern medicine. Therapies aimed at reducing serum LDL cholesterol are currently considered to be a... A Colpo ...
[9]. Doi, T., Langsted, A. & Nordestgaard, B. G. Dual elevated remnant cholesterol and C-reactive protein in myocardial infarction, atherosclerotic cardiovascular disease, and mortality. Atherosclerosis 379, 117141 (2023). [10]. Small, A....