贝特类药物是降低 TG 的重要药物,这类药物通过激活过氧化物酶体增殖物激活受体(PPARα),起到降低 TG,升高 HDL-C 的作用,而佩玛贝特就是新型的 PPRAα 激动剂,该药物通过选择性的结合 PPARα 受体调控其表达,从而全面降低血清 TG 水平。 发表在新英格兰医学杂志上的一项临床降脂治疗试验 PROMINENT[5],共纳入 ...
HDL (high-density lipoprotein) ranges chart HDL Ranges (mg/dL)Risk Less than 40 mg/dL (men), less than 50 mg/dL (women) heart disease Greater than 60mg/dL some protection against heart disease LDL (low-density lipoprotein) ranges chart LDL Ranges (mg/dL)Risk Less than 100 optimal 10...
贝特类药物是降低 TG 的重要药物,这类药物通过激活过氧化物酶体增殖物激活受体(PPARα),起到降低 TG,升高 HDL-C 的作用,而佩玛贝特就是新型的 PPRAα 激动剂,该药物通过选择性的结合 PPARα 受体调控其表达,从而全面降低血清 TG 水平。 发表在新英格兰医学杂志上的一项临床降脂治疗试验 PROMINENT[5],共纳入 ...
240 mg/dL and overHigh A cholesterol chart: Total, LDL, HDL, Triglycerides, VLDL It would be more convenient for everybody to interpret their cholesterol test results if only they could provide just one number as a result. Unfortunately, there exist multiple cholesterol types, as well as vari...
A comparison of non-HDL and LDL cholesterol goal attainment in a large, multinational patient population: The Lipid Treatment Assessment Project 2 Objective This study evaluated the success in attaining non-HDL-cholesterol (non-HDL-C) goals in the multinational L-TAP 2 study. Methods 9955 patients...
HDL: High-Density Lipoprotein PICOS: Population,interventions,comparators and outcomes PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses ISI: International Statistical Institute AIS: Acute Ischemic Stroke HPLC: High-performance liquid chromatography NMR: Nuclear magnetic resonan...
HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. N Engl J Med 2007;357:1301-10.Barter P, Gotto AM, LaRosa JC, Maroni J, Szarek M, Grundy SM, Kastelein JJ, Bittner V, Fruchart JC. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular ...
underwent phlebotomy to analyze total cholesterol, direct LDL‐C, HDL‐C, and triglyceride levels that were performed by a central core laboratory. 在研究开始时和在任何患者登记之前,每个参与站点的提供者完成收集提供者和实践特征...
LDL-C 118.4±46.4 mg/dL, and triglycerides 162.1±92.4 mg/dL.#CV risk was estimated by the investigators as "high" or "very high" for 34.3% and 35.4% of patients, respectively, whereas calculated CV risk according to the SCORE chart 1 was "high" or "very high" for 12.6% and 81.8%...
This is a potential cardiovascular risk factor that patients and providers should be aware of. A prospective proof of concept study would further clarify this relationship. Chart 1 Baseline Characteristics and Off-OCP Lipids & Lipoproteins Patient Designation Total Cholesterol LDL-C HDL-C TGs LDL-P...