乳酸脱氢酶基因LDHA,LDHB分别位于___。 A. 15p11-p14;12p12.2-p12.1 B. 11p15-p14;12p12.2-p12.1 C. 11p15-p14;11p12.2-p12.1 D. 11p11-p14;12p12.2-p12.1 E. 11p15-p14;12p11.2-p12.1 相关知识点: 试题来源: 解析 A.15p11-p14;12p12.2-p12.1 ...
乳酸可阻止T细胞和NK细胞中NFAT的活化,使IFNγ产生减少,这与乳酸在炎性环境中促进IFNγ产生的作用相反。 LDHA的表达受HIF1α、MYC和p53调节,可促进上皮-间质转化,血管生成和侵袭增加。LDHB表达下调或缺失是前列腺癌、乳腺癌和胰腺癌等癌症发展中一个重要的早期事...
因此,对LDHA,LDHB以及乳酸代谢的研究有助于进一步探索喉癌发生发展的分子机制,发现肿瘤治疗的潜在靶点.目前,代谢抑制剂与免疫检查点阻断治疗,化疗,放疗和饮食的联合治疗为肿瘤治疗提供了新的治疗方案.但是,肿瘤细胞代谢改变会影响肿瘤微环境(tumor microenvironment,TME),限制免疫应答,从而增加了肿瘤治疗的难度.肿瘤微环境...
患者,女,胸痛10天后来院就诊,心电图检查正常,怀疑为急性心肌梗死,检查一系列生化指标。A、LDHB、LDHC、LDHD、LDHE、LDHA、24~36hB、10~12h
The mRNA of both LDHA and LDHB were expressed and no significant difference was observed in prepubertal testes. The mRNA levels of LDHB significantly increased during testicular development. In the adult testis,LDHA mRNA was not expressed. Expression studies revealed the presence of different LDH ...
Lactate Dehydrogenase: LDHA, LDHB and LDHC 来自 Wiley 喜欢 0 阅读量: 152 作者: Johana Vázquez‐Matías,HW Mohrenweiser 展开 出版社: American Cancer Society 摘要: This article has no abstract. Keywords: lactate dehydrogenase: LDHA, LDHB and LDHC 展开 关键词: lactate dehydrogenase: LDHA, ...
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lactate dehydrogenase: LDHA, LDHB and LDHCThis article has no abstract. Keywords: lactate dehydrogenase: LDHA, LDHB and LDHCJohana Vázquez‐MatíasLawrence Livermore National Laboratory Livermore CaliforniaHarvey W MohrenweiserLawrence Livermore National Laboratory Livermore California...
Mdluli K, Booth MP, Brady RL, Rumsby G (2005) A preliminary account of the properties of recombinant human glyoxylate reductase (GRHPR), LDHA and LDHB with glyoxylate, and their potential roles in its metabolism. Biochim Biophys Acta 1753(2):209–216. : 10.1016/j.bbapap....
Further data on chromosomal assignments of pig enzyme loci LDHA, LDHB, MPI, PEPB and PGM1, using somatic cell hybrids.doi:10.1111/j.1365-2052.1986.tb00725.xH. RyttmanP. TheboI. GustavssonB. GahneR. K. JunejaBlackwell Publishing Ltd...