It reversibly converts lactate into pyruvate,with the concomitant interconversion of NADH and NAD+.Intended Use:Measurement of released LDH in culture mediumEvaluation of cytotoxicity effect of test compoundsSensitivity:~100 cellsSample Type:Adherent or Suspension CellsTest Principle:The LDH-Cytotoxicity ...
241.66K 文档页数: 20页 顶/踩数: 0/0 收藏人数: 3 评论次数: 0 文档热度: 文档分类: 待分类 文档标签: KitkitLDHKITKit40 .roche-applied-science CytotoxicityDetectionKit (LDH) yVersion08 Contentversion:February2011 Anon-radioactivealternativetothe[ 3 H]-thymidinereleaseassayandthe [ 51 Cr]-releas...
These results provide proof-of-principle that suppressing LDH-A can provide a way of altering the activity of non-glycolytic NAD þ -dependent enzymes such as SIRT1 in a cancer-selective manner. Our results showing that suppressing LDH-A affects cancer cell SIRT1 activity are consistent with ...
In principle, while LDH56 can adsorb 50% more BSA, LDH88 has a higher rate of protein adsorption at lower LDH–BSA mass ratios (Figure 4). Figure 3. Size evolution of LDH–BSA after the physisorption of increasing amounts of BSA on LDH. Conjugates obtained by combining mass ratios of ...