核糖衣壳与Z基质蛋白相互作用并在细胞膜上发芽,从而使病毒体从被感染的细胞中释放出来 淋巴细胞脉络丛脑膜炎病毒是第一种沙粒病毒,全称淋巴细胞性脉络膜脑膜炎哺乳动物沙粒病毒(Lymphocytic choriomeningitis mammarenavirus,LCMV),于1933年由查尔斯·阿姆斯特朗(Charles Armstrong)在圣路易斯进行的一次流行病研究中分离出。尽...
LCMVmemory Bcellsresidual antigenInfection of C57BL/6 mice with lymphocytic choriomeningitis virus (LCMV) strain Armstrong (Arm) induces an acute infection with rapid virus clearance by CD8+ Tcells independently of CD4+ Tcell help. Residual viral antigen may, however, persist for a prolonged time...
Subsequently, we demonstrated that the QPCR assay can detect LCMV in tissues of CD40L -/- mice during a low grade chronic infection with LCMV armstrong. Finally, we improved the assay further such that it was approximately 1000-fold more sensitive than plaque assay for detection of the presence...
Armstrong 53b (Arm53b); baculovirus Autographa californica GP64 (GP64); charge-coupled device (CCD); dystroglycan (DG); feline immunodeficiency virus (FIV); glycoprotein precursor (GP-C); firefly luciferase (Luc); lymphocytic choriomeningitis virus (LCMV); nuclear targeted β-galactosidase (ntLacZ...
LCMV Infection Mice were infected by intraperitoneal injection of 104 pfc of Armstrong 3 LCMV at 6 weeks of age. A single cohort of 5 mice was injected and followed over time. Mice were sacrificed and their LCMV specific repertoire was analyzed as below. Purification of LCMV specific CD8+ ...
Mice infected with the rapidly cleared LCMV Armstrong strain at 2 × 106 pfu i.v., had a similar disease course as compared to the low dose LCMV cl-13 infection (data not shown). Having observed this dose-dependent pattern of morbidity and illness in LCMV cl-13 infected mice we ...
LCMV Armstrong Chemicals, peptides, and recombinant proteins H-2D(b) LCMV NP 396-404 FQPQNGQFI NIH Tetramer Core Facility H-2K(b) LCMV NP 205-212 YTVKYPNL NIH Tetramer Core Facility H-2D(b) LCMV GP92-101 CSANNSHHYI NIH Tetramer Core Facility H-2A(b) LCMV GP66–77 DIYKGVYQ...
Albert Einstein(阿尔伯特·爱因斯坦,1879-1955) 2386 播放洞见历史 述古道今,中外古今人事与古史杂谈 收藏 下载 分享 手机看 登录后可发评论 评论沙发是我的～选集(52) 自动播放 [1] Louis Armstrong(路... 7351播放 03:55 [2] Fred Astaire(弗雷德·... 2646播放 03:55 [3] Johann Sebastian...
淋巴细胞脉络丛脑膜炎病毒是第一种沙粒病毒,全称淋巴细胞性脉络膜脑膜炎哺乳动物沙粒病毒(Lymphocytic choriomeningitis mammarenavirus,LCMV),于1933年由查尔斯·阿姆斯特朗(Charles Armstrong)在圣路易斯进行的一次流行病研究中分离出。尽管不是流行性脑膜炎的爆发原因,但已证明LCMV是非细菌性或无菌性脑膜炎的原因。