The high sensitivity afforded by coupling HPLC with tandem mass spectrometry (MS-MS) has made it the technique of choice in this environment, but it is subject to the following limitations when reversed phase liquid chromatography (RPLC) is us...
Liquid chromatography coupled to triple quadrupole tandem mass spectrometry (LC–MS–MS) in multiple reaction monitoring (MRM) mode is widely considered as the gold standard for pesticide analysis. In this article recent developments in LC–MS–MS technology to meet increasing regulatory demands and ...
We recently spoke to Gary Duncan and Wendy Russell of the Rowett Institute of Nutrition & Health in Aberdeen, Scotland, about the significance of phytochemical bioavailability to human health and the important role of liquid chromatography linked to tandem mass spectrometry (LC–MS-MS...
mass spectrometry (LC–MS) methodology ‐ for metabolite identification, with drug metabolite identification being a challenging area of researchelucidation of biotransformation pathways of drug candidate ‐ understanding its physical and biological effectsin silico tools, modern data‐processing software ...
MS‐based mass defect filter approachMDF applicability in different drug biological matricesIntroduction What is Mass Defect? Concept of MDF Implementation of MDF Applications of MDF in Metabolite Identification MDF in Conjunction with Control Sample Comparison Comparison of MDF with Precursor Ion Scan and...
The chromatographic process performed shows the advantages of off-line MDLC technique over on-line approaches, which include high flexibility, and ability to reanalyze sample fractions.Dolman, Basvan Ling, RobertSneekes, Evert-JanEeltink, SebastiaanSwart, RemcoLC-GC North America...
Accurate screening of these samples is critical in regulated environments such as food and animal-feed analysis.doi:http://www.chromatographyonline.com/lcgc/article/articleDetail.jMarkus KellmanAndreas WieghausHelmut MuensterLester TaylorDipankar GhoshSpecial ...
Detection of ovalbumin in egg white, whole egg and incurred pasta using LCeESI-MS/MS and ELISA. Food Res Int 2013;52:526e34.Azarnia S , Boye JI , Mongeon V and Sabik H , 2013 . Detection of ovalbumin in egg white, whole egg and incurred pasta using LC-ESI-MS/MS and ELISA . ...
Liquid chromatography–mass spectrometry (LC–MS) is a popular technique for the analysis of wine. This article gives an overview of wine analysis and new insights this technique has revealed regarding the composition of wine, possible health benefits, customer safety and the understanding of ...
This article describes a simple, more convenient method than traditional solid-phase extraction (SPE)-based methods for highly sensitive PPCP detection using triple quadrupole liquid chromatography–mass spectrometry (LC–MS–MS).Joe AnacletoZicheng Yang...