Human LBX2-AS1 qPCR Primer Pair,即人LBX2-AS1 qPCR引物对,主要用于基于SYBR Green的qPCR、One-Step qRT-PCR或semi-quantitative PCR。本引物为预先设计、经过qPCR验证、预混的引物对。 qPCR (Quantitative PCR)即定量PCR,也称实时荧光定量PCR或实时定量PCR (Real-time quantitative PCR)、实时PCR (Real-time PCR...
LBX2-AS1Colorectal cancerM6A5-FUceRNARecent reports suggest that the long non-coding RNA LBX2 antisense RNA 1 (LBX2-AS1) acts as an important regulator in cancer progression, but its significance in colorectal cancer (CRC) remains undetermined. LBX2-AS1 expression levels in CRC were determined...
摘要 目的基于生物信息学角度探讨长链非编码RNA(LncRNA)LBX2反义RNA1(LBX2-AS1)对结肠癌预后的影响并进行初步验证。方法在基因表达交互分析(GEPIA)数据库查找并明确与结肠癌预后密切相关的基因LBX2-...展开更多 Objective To explore the effect of long noncoding RNA(LncRNA)LBX2 antisense RNA 1(LBX2-AS1)...
2021 Jan; 25(2):1178-1189.JCAbstract LBX2-AS1 is a long non-coding RNA that facilitates the development of gastrointestinal cancers and lung cancer, but its participation in ovarian cancer development remained uninvestigated. Clinical data...
Through bioinformatic analyses, dual-luciferase reporter assay, RIP and Western blot, the regulation of LBX2-AS1 and miR-491-5p on the target gene LIF was identified.Results:LBX2-AS1 was upregulated in glioma samples and cell lines, and its transcription was promoted by binding to the ...
Function assays proved that LBX2-AS1 down-regulation restricted the proliferation ability. Then, we unveiled the LBX2-AS1/miR-219a-2-3p/FUS axis. Additionally, LBX2-AS1 positively regulated LBX2 mRNA stability via FUS. LBX2 transcriptionally modulated LBX2-AS1. In the end, rescue and in ...
表明LBX2-AS1是一种致癌性的lnc RNA,在胶质瘤中表达水平上调,并与患者预后相关,但其在胶质瘤中的作用机制尚不清楚.本研究首先检测了LBX2-AS1在胶质瘤细胞,组织中的表达情况,在此基础上进一步探讨了其致瘤作用及潜在机制.方法:1.通过分析TCGA,CGGA及GEO(GSE151352)中胶质瘤样本的RNA-seq数据,筛选出LBX2-AS1在...
LBX2-AS1gliomaproliferationmigrationLong non-coding RNAs (IncRNAs) have been proposed to play pivotal roles in the tumorigenesis of various malignant tumors.Previous studies have found that IncRNA LBX2-AS1 is involved in the progression of various tumors.However,currently,the expression and exact ...
Retraction Note to: Long non-coding RNA LBX2-AS1 enhances glioma proliferation through downregulating microRNA-491-5pdoi:10.1186/s12935-020-01712-yLINCRNAGLIOMASThis article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12...
目的探讨长链非编码RNA(lncRNA)LBX2-AS1通过表皮生长因子受体(EGFR)信号通路调控胶质瘤细胞增殖,迁移及凋亡的机制.方法2018年4月至2021年8月,将脑胶质瘤U251细胞(简称U251细胞)分为对照组和观察组,每组4株,对照组采用常规培养,观察组利用靶向LBX2-AS1的特异性小干扰RNA(siRNA)转染.采用四甲基偶氮唑盐法检测U...