This research was funded by the Ministero della Salute, Ricerca Corrente—linea 1 and 5 per Mille—Progetto 5M-2020-23682104; the European Commission—Horizon 2020 (EU project 101003544—CoNVat); Innovative Medicines Initiative 2 Joint Undertaking (JU) with support from European Union’s Horizon 20...