The median time to Cmax of balsalazide is about 2 hours. In contrast, Cmaxvalues of mesalazine (2.62 µmol/L) and 4-ABA (<0.096 µmol/L) were achieved 9 and 10 hours after a single dose of balsalazide 2.25g. The systemic uptake of balsalazide and its metabolites appears to ...