Purpose: The human cornea is essential for vision, providing structural integrity and refractive power to the eye. Recent advancements have deepened our understanding of the corneal molecular composition, yet the role of intrinsically disordered proteins within the cornea is unexplored.Methods: We ...
The elasticity mapping of individual layers in the cornea using non-destructive elastography techniques advances diagnosis and monitoring of ocular diseases and treatments in ophthalmology. However, transient Lamb waves, currently used in most dynamic optical coherence and ultrasound elastography techniques,...
The purpose of studying this kind of spherical structures obeys to the development and application of mathematical methods for the study of the cornea and other similar soft tissues. In the present paper, first the AHM technique is used to evaluate the elastic properties of a two-layer laminated...
While using 32-site multielectrode arrays in the mPFC of awake, head-restrained wildtype mice, we stimulated the eyes with diffused light at 7 intensities spanning a 6-log range, covering the operational ranges of rods, cones, and melanopsin19,21(Supplementary Fig.1a, b). At each intensity,...
The corneas were removed or punctured and the eyes were immersed immediately in 4% paraformaldehyde in 0.1 M cacodylate buffer (pH 7.4) for 15 minutes to overnight at 4°C. Best results were obtained using eyecups fixed for 15–30 minutes. Eyecups were rinsed in phosphate buffered saline ...
MEMS applications include the following areas (Kostsov, 2009): - microoptoelectromechanics (displays, adaptive optics, optical microswitches, fast- response scanners for cornea inspection, diffraction gratings with an electrically tunable step, controlled two- and three-dimensional arrays of micromirrors...
14. The pharmaceutical composition of claim 10 formulated for topical application to eye and capable of passing through the cornea and into an intraocular space in the absence of penetration enhancer. 15. A method for treating an eye disease or disorder comprising administering a polypeptide of clai...
which could be used to assess irregularities frequently seen in many layered ocular structures (e.g. retina, iris, cornea) under pathologic circumstances such as DME, Age-Related Macular Degeneration, Epiretinal Membrane (ERM)24, Vitreoretinal Interface abnormalities, Fuchs uveitis in Anterior Segment...
Published: xx xx xxxx Jeffrey C. Everts1 & Miha Ravnik1,2 Charged surfaces in contact with liquids containing ions are accompanied in equilibrium by an electric double layer consisting of a layer of electric charge on the surface that is screened by a diffuse ion cloud in the bulk ...
Recently, tear film lipid layer has received a lot of attention as it was found that more than 80% of the dry eye sufferers report symptoms of meibomian gland dysfunction (MGD), a condition associated with qualitative and quantitative abnormalities in the TFLL [3]. This is because TFLL, ...