Latent TGF-β binding protein-1, -3 and -4 bind latent TGF-β. TGF-βs are normally secreted as latent complexes, consisting of the mature TGF-β dimer non-covalently bound to its processed propeptide dimer plus a latent TGF-β binding protein. The latent TGF-β binding protein is ...
Latent TGFβ binding proteins Extracellular matrix Latency associated protein TGFβ activation Introduction The LTBPs are a group of extracellular multi-domain proteins with several unique biological properties. They contain a number of modular domains including tandem arrays of calcium binding (cb) EGF ...
et al. Latent TGF-βbinding protein-2 is essential for the development of ciliary zonule microfibrils. Hum Mol Genet 23, 5672–5682 (2014). 14. Gibson, M. A. et al. Bovine latent transforming growth factor beta 1-binding protein 2: molecular cloning, identification of tissue isoforms...
摘要: •We describe structures and interactions of the four latent transforming growth factor beta binding proteins (LTBP) proteins.•The biological functions of the four LTBPs关键词: Latent TGFβ binding proteins Extracellular matrix Latency associated protein TGFβ activation ...
Integrin αVβ6-mediated activation of latent TGF-β requires the latent TGF-β binding protein-1 Transforming growth factor-βs (TGF-β) are secreted as inactive complexes containing the TGF-β, the TGF-β propeptide, also called the latency-associated... Justin,P.,Annes,... - 《Journal...
Latent TGF-β binding protein LTBP-1 contains three potential extracellular matrix interacting domains M, Bruckner-Tuderman L, Keski-Oja J (2001) Latent TGF-beta binding protein LTBP-1 contains three potential extracellular matrix interacting domains. J... U Christine,H Marko,BT Leena,... - ...
Increased expression of latent TGF-beta binding protein-1 and fibrillin-1 in human uterine leiomyomata. Mol Hum Reprod 2007; 13(5):343-349.Increased expression of latent TGF- binding protein-1 and fibrillin-1 in human uterine leiomyomata. Zhao Yangyu,Wen Yan,Polan Mary Lake,Qiao Jie,H. ...
latent TGF-beta-binding protein 3 information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
Latent transforming growth factor-β (TGF-β) binding protein (LTBP)-1, which is easily secreted, has been shown to enhance the secretion of TGF-β. Here we show that another member of the LTBP family, LTBP-3, is not secreted by several cell types, but secretion occurs after coexpression...
Latent transforming growth factor-beta 1 and its binding protein are components of extracellular matrix microfibrils. We studied the localization of latent transforming growth factor-beta 1 (TGF-beta 1) and its binding protein (LTBP-1) in the extracellular matrix of cultur... J Taipale,J Sahar...