Reports that in early-stage human immunodeficiency virus (HIV) disease there is a dichotomy between the levels of viral burden and virus replication in peripheral blood versus lymphoid organs. Profiles of 12 patients in different stages of HIV infection who were analyzed for viral burden; Analysis ...
Pediatric HIV infection: diagnostic laboratory methods. The diagnosis of HIV-1 infection in infants and children continues to present challenges. Currently available virologic assays are sensitive and specific a... Lujan-Zilbermann,Rodriguez,Emmanuel - 《Fetal & Pediatric Pathology》 被引量: 15发表: ...
latent hiv-1 infection in enriched populations of... MJ Mcelrath,RM Steinman,ZA Cohn,... 被引量: 0发表: 2018年 Factors influencing T-cell turnover in HIV-1–seropositive patients The dynamic basis for T-cell depletion in late-stage HIV-1 disease remains controversial. Using a new, non...
In a prospective sample, one of 20 patients was found to have a past or current S. stercoralis infection. Findings suggest that screening for such infections should be a part of primary care for HIV-infected patients originating from endemic areas.Medical Journal of AustraliaGurry, Greta A...
Latent HIV-1 infection of resting CD4 + T cells provides a long-lived reservoir of viral persistence in patients on antiretroviral therapy (ART). Intensive research into the mechanisms of HIV-1 latency has led to the identification of numerous potential therapeutic targets that might be exploited ...
Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals... S Moron-Lopez,S Telwatte,I Sarabia,... - 《Plos Pathogens》 被引量: 0发表: 2020年 HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regu...
HIV-1 can establish a state of latent infection at the level of individual T cells. Latently infected cells are rare in vivo and appear to arise when activated CD4(+) T cells, the major targets cells for HIV-1, become infected and survive long enoughHIV...
The study proposed to identify the prevalence of latent tuberculosis infection (LTBI) in persons living with HIV/AIDS (PLWHA), associated factors, and progression to active tuberculosis among the identified cases. This was an epidemiological and descriptive study. The study population consisted of PLWH...
The highly active antiretroviral therapy (HAART) can certainly decrease the plasma viral load below the detec- tion limit; however, complete elimination of HIV infection remains far out of reach. The major hindrance in this direction is the latent HIV infection in cell subpopulations where anti-...
A major barrier to the elimination of HIV-1 infection is the presence of a pool of long-lived, latently infected CD4+ memory T-cells. The search for treatments to re-activate latent HIV to aid in clearance is hindered by the incomplete understanding of the mechanisms that lead to transcripti...