Late-life depression (LLD) is both a prevalent and life-threatening disorder, affecting up to 13.3% of the elderly population. LLD can be difficult to identify because patients mainly consult their general practitioner (GP) for somatic complaints. Moreover, patients may be hesitant to express ...
抑郁症是老年人常见的精神障碍之一。老年抑郁症 (late life depression,LLD)广义上指年龄在60岁以上的抑郁症病人,狭义上是指首次起病年龄在60岁之上的抑郁症病人,以持久的情绪低落为主要临床症状的一种精神障碍性疾病,其危害性不容忽视,如不及时诊治将严重影响老年人生活质量,导致老年人精神残疾,抑郁严重的老...
Late-life depression (LLD) is associated with an increased risk of developing dementia; however, it is not known whether individuals with a history of LLD exhibit a more rapid rate of cognitive decline. We aimed to determine whether those with LLD experienced faster cognitive decline compared with...
Late-life depression (LLD) may influence the presence and extent of cognitive deficits among older adults with SVD, creating a vulnerability that contributes to the clinical expression of cerebrovascular pathology. Cognitive deficits are common in LLD, and often involve impairments in processing speed,...
ContextCognitive impairment in late-life depression (LLD) is highly prevalent, disabling, poorly understood, and likely related to long-term
1 Late-life depression (LLD) is common. In a 2013 meta-analysis,2 estimated current and lifetime prevalence rates of major depressive disorder among older adults were 3.3% and 16.5%, respectively; current prevalence of significant LLD symptoms (ie, encompassing major and minor depression) is ...
Major depression in the elderly is a heterogeneous disorder that presents with a constellation of cognitive and affective symptoms. Neuroimaging has helped elucidate the contributions of dorsal-cognitive and ventral-affective brain regions to the pathophysiology of late-life depression (LLD). Functional co...
Depression is associated with an increased risk of dementia [1]. Due to the heterogeneity of late-life depression (LLD), many researchers have attempted to classify its phenotypes [2]. Among these, late-onset depression (LOD) and early-onset depression (EOD) distinguished by the age of first...
Late-life depression (LLD) is frequently associated with cognitive impairment and increases the risk of subsequent dementia. Cerebrovascular disease, deep ... KA Jellinger - 《Journal of Neural Transmission General》 被引量: 18发表: 2013年 Lifestyle-related risk factors in dementia and mild cogniti...
Late-life depression (LLD) in the elderly was reported to present with emotion dysregulation accompanied by high perceived loneliness. Previous research has suggested that LLD is a disorder of connectivity and is associated with aberrant network properties. On the other hand, perceived loneliness is ...