MENTAL FUNCTION AND GROWTH IN CHILDREN WITH EARLY (E) VS. LATE (L) ONSET END-STAGE LIVER DISEASE (ESLD)Pediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to ...
liver cancer, need for liver transplant and premature mortality,” study investigator Stephen Harrison, MD, of Pinnacle Clinical Research and Summit Clinical Research in San Antonio, said in the press release. “With no approved treatment, this disease represents one of the most urgent unmet needs ...
Liver-stage genetically attenuated malaria parasites (GAPs) are powerful immunogens that provide protection against sporozoite challenge. We previously generated two late liver-stage-arresting GAPs by deleting the stearoyl-CoA desaturase (Scd) or sporozoite conserved orthologous transcript 1 (Scot1) genes ...
Asymptomatic patients with abnormal PFTs should be closely monitored for the development of respiratory symptoms; an early recognition of airflow obstruction allows the initiation of treatment at a potentially reversible stage. Obliterative bronchiolitis (OB), the best characterized obstructive syndrome, has...
Endometriosis is a chronic inflammatory gynecological disease. Previous studies have explored relationships between endometriosis and the microbiota, but none have focused on differences in gut microbiota between early-stage and late-stage endometriosis patients or their connections to dysmenorrhea symptoms. Th...
“Living with PBC can be very challenging for many people. The fear of the disease progressing hangs over you, and you have to manage as best you can with the daily symptom burden, symptoms that can sometimes be so debilitating it takes every ounce of strength to get through another day,...
Intervertebral disc degeneration (IVDD), a common process during natural aging, results in severe spinal symptoms, notably lower back pain (LBP), and has emerged as a leading cause of disability worldwide1,2. Previous studies have shown that the degeneration and progression of the local inflammato...
Seventy-six people with advanced follicular lymphoma (stage III & IV) who had not yet been treated for their disease participated in the eight year study. Results showed 95% responded positively. 75% had a complete disappearance of any sign of cancer. Overall survival was 86%. Fifty percent ...
symptomatic and anaemic and had been previously treated with an FDA-approved JAK inhibitor. The study was designed to evaluate the safety and efficacy of momelotinib for the treatment and reduction of the key hallmarks of the disease: symptoms, blood transfusions (...
In the pre-cancerous condition, all is prepared. The liver is sufficiently damaged and the other organs of the intestinal tract are damaged enough and then later the symptoms appear. Until then we have the pre-cancerous condition and this condition cannot be cured with hormones and enzymes, ...