Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective therapy for decades. Although glucose and glutamine are the major fuels that drive GBM growth and invasion, few studies have targeted these fuels for therapeutic management. The glutamine antagonist, 6-diazo-5...
Anti-angiogenic and anti-tumorigenic effects of 34.5ENVE are currently being assessed in model of late stage ovarian cancer. 790. Combined Delivery Carrier of Anticancer Drug and siRNA for the Treatment of Glioblastoma Na Yi, Hyun Ah Kim, Minhyung Lee Department of Bioengineering, College of ...
Seventy-six people with advanced follicular lymphoma (stage III & IV) who had not yet been treated for their disease participated in the eight year study. Results showed 95% responded positively. 75% had a complete disappearance of any sign of cancer. Overall survival was 86%. Fifty percent ...
2023). In glioblastoma, Du et al. reported that PD-L1-driven immune evasion is regulated by the miR-10b-5p-mediated regression of TET2 (Du et al. 2023). The role of miR-10b-5p as a target for mediating sarcoma progression has also been reported (Yoshida et al. 2023). Dai et al....
Glioblastoma EO2401 (EO) therapeutic vaccine for patients (pts) with recurrent glioblastoma (GB): phase 1/2 ROSALIE study David A. Reardon Poster #303P Poster Session: CNS Tumours Saturday, September 10, 2022 12:00-13:00 CEST ...
Significantly higher levels of water-soluble S-100 protein per mg of water-soluble protein have been shown in normal human cerebral white matter and astrocytomas of grades I鈥揑II and neurinomas than in normal grey matter, glioblastomas,... KG Haglid,D Stavrou,L Rönnbäck,... - 《Jo...
We found 3124 DEGs, many of which were highly correlated with Braak stage and cerebral atrophy. Pathway Analysis revealed the most perturbed pathways to be (a) nitric oxide and reactive oxygen species in macrophages (NOROS), (b) NFkB and (c) mitochondrial dysfunction. NOROS was also up-...
Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma.CNS cancerCancer metabolismGlioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective therapy for decades. Although glucose and glutamine are the ...