prognosisrelapse ratesObjectives:Early-onset anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDARE) differs from late-onset anti-NMDARE regarding clinical characteristics. Until recently, research focusing on prognosis of elder adults has been scarce and showed inconsistent results. This study ...
Multiple personality factors increase risk for MDD. A recent meta-analysis controlling for baseline depressive symptoms found that low extraversion, high neuroticism, and low conscientiousness predicted depressive symptoms 5 years later32. Research on stroke survivors14, individuals with Parkinson’s Disease...
A late-onset Alzheimer’s disease (LOAD) framework is proposed from healthy cognitive aging to late-stage Alzheimer’s disease (AD), presenting the following testable hypothesis: Glial senescence accumulation, particularly requiring increased senescent microglia burden, may correspond to clinical LOAD prog...
BMC Cancer (2021) 21:634 https://doi.org/10.1186/s12885-021-08353-y RESEARCH Open Access Radiographic features and prognosis of early- and late-onset non-small cell lung cancer immune checkpoint inhibitor- related pneumonitis Aiben Huang1†, Yang Xu2†, Xuelei Zang3†, Chongchong Wu4,...
Background: Despite having the same histopathological characteristics, early-onset and late-onset Alzheimer's disease (AD) patients show some distinct clinical and neuropsychological profiles. Early Onset Mild Cognitive Impairment (EOMCI) is a less characterized group. The aim of this study is to cha...
Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia; it disproportionally affects women in terms of both incidence rates and severity of progression. The cellular and molecular mechanisms underlying this clinical phenomenon remain elusive and ill-defined. ...
serum uric acid and clinical progression in parkinson disease:practice parameter: diagnosis and prognosis of new-onset parkinson disease (an evidence-based... parkinson disease (pd) is the second most common neurodegenerative disorder, with a prevalence and incidence rate that increases significantly wit...
individuals with Parkinson’s Disease33, and nonclinical older adult samples34has found similar associations, suggesting that these effects are also observed in late life. Another personality characteristic associated with resilience is grit, defined as “perseverance and passion for long-term goals” in...
are effective in depression of Parkinson’s disease and their efficacy needs to be assessed in these two syndromes. Computerized cognitive remediation targeting functions of the cognitive control network may improve both executive functions and depressive symptoms of late-life major depression. Significant...
Different mutations in the TTR gene are associated with distinct age of onset, disease penetrance, clinical phenotype, prognosis and clinical outcome9. In addition to familial TTR- associated forms of amyloid, senile systemic amyloidosis (SSA) is a nonhereditary, late onset sporadic form of TTR ...