Extensive evidence indicates that the nucleus accumbens is involved in spatial learning and memory tasks. There has been relatively little inquiry, however, into which of the two anatomically and functionally distinct subregions of the nucleus accumbens (the shell and the core) mediate this involvement...
Late onset multiple sclerosis: clinical characteristics, prognostic factors and differential diagnosis Late onset multiple sclerosis (LOMS), defined as the first presentation of clinical symptoms in patients over 50, is not a rare phenomenon as previously th... V Martinelli,M Rodegher,L Moiola,......
People at risk of developing late onset diabetes are primarily older adults who are overweight and do not get adequate exercise. People with this condition can develop symptoms like fatigue, thirst, frequent urination, and blurred vision. Medical evaluation will reveal increasedblood glucose, indicative...
Late-Onset Neurological Symptoms in a Child With Diarrhea-Associated Hemolytic Uremic SyndromeNo abstract is available for this article.doi:10.1111/1744-9987.12243Krisztina RusaiKatharina GruberStephanie DufekRainer SeidlThomas Mueller㏒achererJohn Wiley & Sons, Ltd.Therapeutic Apheresis & Dialysis...
(ERT).3,4 In contrast, late-onset Pompe disease (juvenile and adult) is caused by a partial deficiency of acid alpha-glucosidase and has a more insidious course.5–8 Typical symptoms in this form of the disease consist of slowly progressive proximal muscle weakness and respiratory difficulties...
A similar delay in the onset of CPSP was recently reported in rats in which a focal ischemic lesion in the thalamus was induced by injection of endothelin-134. Unfortunately, this animal model exhibited thermal hyperalgesia but not mechanical allodynia, which is one of the most common symptoms ...
et al. Physical health and the onset and persistence of depression in older adults: an eight-wave prospective community-based study. Psychol Med.2000;30:369-380.Google Scholar 9. Unützer J, Patrick DL, Diehr P. et al. Quality adjusted life years in older adults with depressive symptoms ...
Toyota, YIkeda, MShinagawa, SMatsumoto, TMatsumoto, NHokoishi, KFukuhara, RIshikawa, TMori, TAdachi, H
Late onset Pompe disease (LOPD) is a slow, progressive disorder characterized by skeletal and respiratory muscle weakness. Enzyme replacement therapy (ERT) slows down the progression of muscle symptoms. Reliable biomarkers are needed to follow up ERT-treated and asymptomatic LOPD patients in clinical ...
Within the total SP population (n = 534), information on the time to onset of the progressive phase was available for 509 patients. Exacerbations were defined as acute development of new symptoms or worsening of existing symptoms lasting more than 24 hours (ie, Poser and Lublin criteria).31,...