latanoprost (0.005% once daily) was significantly more effective than timolol (0.5% twice daily) in two double-blind, monotherapy trials (8.2 and 8.8mm Hg vs 5.2 and 5.7mm Hg for latanoprost vs timolol at 12 and 2 weeks, respectively). ...
Background: This study aimed to evaluate the non-inferiority and safety of a newly developed preservative-free (PF) multi-dose latanoprost/timolol ophthalmic solution, compared with the benzalkonium chloride (BAK)-preserved fixed combination, in patients with open-angle glaucoma and ocular hypertension...
Latanoprost was more efficacious than the prototype β-blocker timolol at 3 AM, 6 AM, 9 AM, 12 PM, 9 PM, and at midnight. The prostaglandin was also more effective than the topical carbonic anhydrase inhibitor dorzolamide at 9 AM, 12 PM, 3 AM, and 6 AM. Quaranta et al. (2006) ...
travoprost or timolol.10–13 The advent of a patented topical latanoprost formulation with out preservative offered a higher tolerability of prostaglan din glaucoma medication, with relatively fewer symptoms of ocular surface disease that could compromise adherence to treatment.14–19 Given the ...
Purpose: The effectiveness, safety and tolerability of the preservative-free fixed combination of tafluprost and timolol (PF-TTFC) were evaluated over the ... F Oddone,L Tanga,S Giammaria,... - 《Clinical Ophthalmology》 被引量: 0发表: 2024年 A phase II study on the duration and stability...
General Description Latanoprost (Xalatan) is available as a 0.005% sterileophthalmic solution in a 2.5-mL dispenser bottle.Latanoprost is also marketed as a combination ophthalmicproduct with the β-adrenergic blocking agent, timolol,which apparently enhances IOP-lowering by decreasing theproduction of aq...
Objective:To compare treatment persistence and costs with 3 glaucoma treatment sequences (first-line/second-line): latanoprost/latanoprost–timolol (LLT), bimatoprost/bimatoprost–timolol (BBT), and travoprost/travoprost–timolol (TTT), derived from the UK General Practitioner Research Database (UK-GPRD...
(1) Background: The current study aimed to compare two of the most frequently prescribed preservative-free (PF) antiglaucoma drops, (Latanoprost PF vs. Bimatoprost PF) in promoting OSD in patients with POAG. (2) Methods: In this prospective study, 44 eyes from 44 participants were included....
Noninferiority of preservative-free versus BAK-preserved latanoprost-timolol fixed combination eye drops in patients with open-angle glaucoma or ocular hypertension. J Glaucoma. 2019;28(6):498–506. doi:10.1097/IJG.0000000000001248 10. Economou MA, Laukeland HK, Grabska-Liberek I, Rouland JF. ...
In this study, we made a comparative efficacy and safety assessment of two different fixed combinations of drugs, viz., tafluprost/timolol (TAF/TIM) and latanoprost/carteolol (LAT/CAR), by determining their effects on intraocular pressure (IOP) in ocular normotensive monkeys and examining their to...