The mammalian LAT gene encodes an adaptor protein critical for various signal transduction processes, including those initiated by the T cell receptor on T cells and the FcRI receptor on mast cells. As a first step toward understanding the mechanisms responsible for the cell-type restricted ...
第四 It is the first evidence that an FTO fat gene is connected with protection against depression. (这 第一次有证据表明FTO肥胖基因与防止抑郁症相关联),可以推断 出,以前没有证据表明FTO肥胖基因所起的作用。 故选C 30.D 细节理解题。 通读最后一段可知,本段介绍了女演员LisaRiley 虽然比较胖,但却...
Abstract:We previously constructed a herpes simplex virus 1 (HSV-1)UL7mutant virus (M1) and showed that a partial deletion mutation of theUL7gene led to a lower proliferative rate and an attenuated phenotype. Using t...
protein-coding gene 同源简称(alias symbol) LAT1 基因家族代码(gene_family_id) [HGNC][GenScript] omim代码 602354 entrez码 27040[Vega] ensembl基因码 ENSG00000213658[Ensembl] 基因家族(gene family) refseq数据库代号 NM_014387 更多... 基因染色体位置 ...
The latency associated transcript (LAT) gene is the only viral genomic region that is abundantly transcribed during herpes simplex virus type 1 (HSV-1) neuronal latency. As such, it may play an important role in HSV-1 latency and/or reactivation. The regulation of the LAT gene is complex ...
The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) gene is required for efficient spontaneous reactivation in the rabbit ocular model. We recently showed that insertion of 1.8 kb of the LAT promoter and the first 1.5 kb of the 8.3-kb primary LAT transcript into a ...
Promoter Hypermethylation of LATS2 Gene in Oral Squamous Cell Carcinoma (OSCC) Among North Indian Population Large Tumor Suppressor (LATS2) gene are Tumor Suppressor gene, linked with epigenetic modifications. LATS2 promoter hypermethylation is an important epigen... H Goel,R Mathur,A Shrivastava,....
Tumours with a LATS2 mutation often also harbour a P53 but not K-RAS gene mutation and were mostly in an advanced stage of development, with regional lymph node involvement. 展开 关键词: LATS2 NSCLC P53 K-RAS MDM2 Mutation Squamous RT-PCR ...
The large tumor suppressor gene ( Lats1) encodes a protein kinase that is highly conserved from fly to human, and plays a crucial role in the prevention of tumor formation by controlling mitosis progression. We have found that in addition to the previously isolated 7.5 kb long form of Lats1...
Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts. We have cloned and characterized LATS2, a novel mammalian homologue of the Drosophila tumor suppressor gene lats/warts. Northern blot analysis showed ubiqu... N Yabuta,...