Lassa virus < virus classificationpublic policy < social scienceLassa fever is an acute zoonotic disease endemic in the African continent. The COVID-19 pandemic has aggravated this situation, as it has increased the fragility of African health systems and redirected resources from other diseases to ...
Infectious materials from patients with the following pathogens: Crimean/Congo haemorrhagic fever, Ebola, Guanarito, Hendra, Herpesvirus simiae (B virus), Junin, Kyasanur forest disease,Lassa fever,Machupo, Marburg, Omsk, Russian spring-summer encephalitis, Sabia and Variola viruses. ...
Wildy’ P.: Classification and Nomenclature of Viruses. Monographs in Virology 5. Basel’ New York: S. Karger 1971. About this Chapter Title Lassa Fever Virus Book Title Lymphocytic Choriomeningitis Virus and Other Arenaviruses Book Subtitle Symposium held at the Heinrich-Pette-Institut für expe...
Yuan Jin1*, Junjie Xu1* and Junjie Yue1* Abstract Background Lassa fever is a hemorrhagic disease caused by Lassa virus (LASV), which has been classified by the World Health Organization as one of the top infectious diseases requiring prioritized resear...
Lassa fever is caused by a single-stranded RNA virus belonging to the Arenaviridae family5. There are currently six main Lassa virus (LASV) clades distributed across different West African countries: clades I–III (Nigeria), clade IV (Sierra Leone, Guinea, and Liberia), clade V (southern Ma...
Lassa fever — the road ahead Robert F. Garry Nature Reviews Microbiology (2023) Molecular mechanism of de novo replication by the Ebola virus polymerase Qi Peng Bin Yuan Yi Shi Nature (2023) Structure of Machupo virus polymerase in complex with matrix protein Z Jun Ma Shuangyue Zhang...
Lassa fever is a neglected tropical disease with a significant impact on the health care system of endemic West African nations. To date, case reports of Lassa fever have focused on laboratory characterisation of serological, biochemical and molecular as
Lassa fever diagnostic assay, which hampers early detection and rapid implementation of existing treatment regimens (e.g. Ribavirin administration). The severity of the disease, ability to be transmitted by aerosol, and lack of a vaccine or therapeutic drug led to its classification as a National ...
Here we will review the characteristics of Lassa virus infection, vaccine strategies, and some of the experimental vaccines. We will mention the potential for postexposure vaccination for prevention of Lassa fever, and will review the use of new technology in standardizing these vaccines....
Our study demonstrates thatthe Ct value on admission has prognostic value and Lassa fever patients treated with ribavirin typically clear the virus within three to four weeks of hospitalization. This kinetics has implications for the design of clinical case management and future clinical trial protocols...