The duration of diuretic effect is 6 to 8 hours. In fasted normal men, the mean bioavailability of furosemide from LASIX Tablets and LASIX Oral Solution is 64% and 60%, respectively, of that from an intravenous injection of the drug. Although furosemide is more rapidly absorbed from the ...
The onset ofdiuresisfollowing oral administration is within 1 hour. The peak effect occurs within the first or second hour. The duration of diuretic effect is 6 to 8 hours. In fasted normal men, the mean bioavailability of furosemide from LASIX Tablets and LASIX Oral Solution is 64% and 60...
Metabolism and Excretion: Minimally metabolized by liver, some nonhepatic metabolism, some renal excretion as unchanged drug. Half-life: 30–120 min (↑ in renal impairment). TIME/ACTION PROFILE (diuretic effect) ROUTEONSETPEAKDURATION PO 30–60 min 1–2 hr 6–8 hr IM 10–30 min unknown ...