China's First Large-Scale Birth Cohort Study Will Start This Year 队列研究中国人口学统计摘要:VIPChina Population Today
Alterations in intestinal microbiota have been identified as a key risk factor in rheumatoid arthritis (RA). This study presents a multidimensional gut microbiota profile from a large cohort of RA patients, stratified by disease stage and treatment regimens, and compared to healthy controls. Our data...
A large-scale population-based longitudinal cohort study was conducted to evaluate the hazard ratio (HR) of RA among 1985 patients with pemphigus relative to 9874 age-, sex-, and ethnicity-matched control subjects. A multivariate Cox regression model was utilized. The incidence of RA was 1.07 ...
www.nature.com/scientificdata OPEN Received: 9 May 2018 Accepted: 20 July 2018 Published: 11 September 2018 Data Descriptor: The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease Minghui Wang et al.# Alzheimer's disease (AD) affects half the ...
Distinct clinical characteristics and risk factors for mortality in female COVID-19 inpatients: a sex-stratified large-scale cohort study in Wuhan, China BACKGROUND. As the coronavirus disease 2019 (COVID-19) outbreak accelerates worldwide, it is highly significant to evaluate sex-specific clinical...
Dietary Habits and Risk of Lung Cancer Death in a Large-scale Cohort Study (JACC Study) in Japan by Sex and Smoking Habit Lung cancer has increased and is the leading cause of cancer death among Japanese males. The associations of dietary habits with the risk of lung cancer de... K Oz...
We collected human gut microbiota datasets of different diseases from the National Center for Biotechnology Information (NCBI) to construct a multipopulation cohort. The keywords we searched in PubMed included ‘gut microbiota’, ‘16S’, ‘human’, ‘stool’ and ‘microbiome’. Only samples from ...
Functional assays based on patient-derived organoids (PDO) are a promising new tool for derisking clinical development of new therapies, but their use has been limited due to small cohort sizes and the absence of systematic validation studies. Using the largest cohort of matched PDOs, ...
Table 1 Large-scale cohort studies with genomic information Full size table How to store and analyze human genome data efficiently? The sequencing data once generated, must be stored in a specific format. In the past, various sequencing formats have been proposed, e.g., CSFASTA/QUAL format. ...
In our prospective cohort, we showed that Japanese patients with AMI could be characterized as (1) having a disease severity comparable with values observed in Western populations and (2) receiving early reperfusion therapy by PCI, which was used widely and safely, but nevertheless (3) exhibiting...