Macrophages, large white blood cells that engulf and destroy potential pathogens, harbor active viral reserves that appear to play a key role in impaired learning and memory in mice infected with a rodent version of HIV. Chao-Jiang Gu of Icahn School of Medicine at Mount Sinai, New York, and...
e.g., dendritic cells and macrophages) that engulf large and essential particles. Viral entry by this pathway typically involves the formation of large extracellular projections, and the internalized virus is taken into a phagosome. Actin and RhoA are typically necessary for this process...