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Correlation heatmap between samples was performed in R using the top 100 marker genes for each sample using the FindAllMarkers() function followed by the selection of the top 100 marker genes using the top_n() function withn = 100 and wt = avg.logFC. The correlation analysis was...
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Mechanistic models of how single cells respond to different perturbations can help integrate disparate big data sets or predict response to varied drug combinations. However, the construction and simulation of such models have proved challenging. Here, w