Our initial clinical impression favored a mass of malignant origin. Of clinical importance, this case emphasizes the need for vaginal examinations in selected adolescent patients. In addition, we as physicians must not be complacent when a pelvic ultrasound is reported as unremarkable.(Figures 1 and...
The first case of non-functional tumor progression was a female patient who was initially submitted to cervical surgery in 1993 and presented MEN1-related tumors: a non-functioning pituitary adenoma, multiple pancreatic endocrine tumors, as well as a goiter. No calcium abnormality was present at ...
RSK3 switches cell fate: from stress-induced senescence to malignant progression Anda Huna Jean-Michel Flaman David Bernard Journal of Experimental & Clinical Cancer Research (2023) Biological and clinical implications of FGFR aberrations in paediatric and young adult cancers Lauren M. Brown Paul...
The four most common primary CNS tumours in adults include meningiomas (34.7%), gliomas (30%), pituitary adenomas (13.5%) and nerve sheath tumours (8.5%) (CBTRUS, 2012). Gliomas are intrinsic CNS tumours derived from glial cells. Highly malignant glioblastomas are the most common type, with...
in terms of clinical care and surveillance since a strong association has been observed between the presence of internal neurofibromas and the occurrence of malignant peripheral nerve sheath tumours (MPNSTs) (Tucker et al.2005; Mautner et al.2008; Nguyen et al.2014). MPNSTs are very aggressive...
Although this RGDKGE-containing collagen fragment selectively bound to vascular endothelial cells and stimulated angiogenesis dependent in part on the transcriptional coactivator yes-associated protein (YAP), it is not known whether this collagen fragment is generated in malignant tumors or whether it play...
Cases of cancer were defined as malignant diseases or CNS tumours regardless of the histology. Topography codes 70–71, 722–729, 751–753 of the International Classification of Diseases (ICD) for Oncology—3rd revision-defined CNS tumours; the morphology codes used for leukaemia (including myelo...
Since they exhibit a significant increase in body mass over time, they are particularly prone to malignant ventricular dysrhythmias [26,28]. In addition, the time points of coronary occlusions are unpredictable [26]. Pigs are also used to evaluate the biomaterial for bone regeneration and dental...