In this article, we review the small and large animal models used in pre-clinical hearing research such as mice, rats, chinchilla, guinea pig, rabbit, cat, monkey, dog, pig, and sheep to humans, and compare the physiology, inner ear anatomy, and some of their use as model systems for...
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The dataset consists of a collection of around 135,000in vivoassays that relate to disease-, phenotype- or toxicity-relevant animal models and have been typically been performed on target organisms such as Rat (45%) and Mouse (37%) as well as Human (5%), Dog (4%), Guinea Pig (4%)...
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Likewise, the base-line abundance of various protein markers may differ between rat, or other animal, and human sources of proteins. Homologous proteins from different species are preferred protein markers for both efficacy and toxicity. While it is very useful to know the quantities of various ...