Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation. Am J Physiol Gastrointest Liver Physiol. 2012;303:G675–85. https://doi.org/10.1152/ajpgi.00152.2012. Article CAS PubMed PubMed Central Google Scholar Chen...
Hence, identifying risk factors which may be associated with GERD and the sex differences among these risk factors is important to decrease the burden on healthcare systems and develop new treatments to improve patient care. Sex differences have been observed in many diseases, including cardiovascular...
Chronic diarrhea is a multifactorial disorder that causes significant psychological distress to patients and economic burden to the healthcare system28. Probiotics are increasingly being prescribed for the management of chronic diarrhea. However, previous intervention studies of probiotic-based diarrhea managem...
Large colonic polyps are associated with advanced dysplasia, but prevalence and characteristics of synchronous polyps in patients with large flat colonic polyps are poorly investigated. This study aims to characterize clinicopathological features of large flat colonic polyps and their impact on occurrence an...
Interestingly, this study found that the P9 intervention decreased the glutamate level in the gut metabolome, while the taurine level increased. Glutamate has been implicated in reshaping the gut microbiota and the overall colonic environment in ways that can be detrimental to host health. Dietary gl...
Probiotics primarily function by modulating the overall bal- ance of the gut microbiota to restore and maintain colonic homeostasis. Thus, dramatic post-probiotic intervention responses are not always anticipated, and a longer duration of intervention may be needed for more substantial effects. In fact...
nutrients Article Dose-Dependent Prebiotic Effect of Lactulose in a Computer-Controlled In Vitro Model of the Human Large Intestine Melanie K. Bothe 1,*, Annet J. H. Maathuis 2, Susann Bellmann 2, Jos M. B. M. van der Vossen 3, Dirk Berressem 4, Annalena Koehler 4, Susann Schwejda...