Figure 1. Five types of white blood cells in the normal peripheral blood. White blood cell Lymphocyte Monocyte Neutrophil Eosinophil Basophil Increase Acute and chronic leukemia, hypersensitivity reaction, viral infection Autoimmune disease, fungal and protozoan infection Chronic inflammation, ...
cytofluorimetric analysis, WBC count and clonogenic assays were employed to monitor circulating cells and to analyze the PBPC harvest. Correlation between different PBPC doses and hematologic toxicity as well as leukocyte and platelet recovery time was attempted. Patients received a median number of 16...
Anemia is characterized by an inability to properly transport oxygen in the blood due to a qualitative or quantitative defect in red blood cells. A quantitative defect is a decrease in the overall number of circulating red blood cells. A qualitative d...
This behavior is mediated by a large and rapid rise in circulating JH. Short days and lower temperatures result in intermediate titers of JH. This results in a long migratory flight. If the insects do not find sufficient food and environmental conditions, the JH concentration drops further and ...
, 12., 13. thy-mus,14 and peripheral blood of immunodeficiency patients15; and recently reported acute T cell lymphoblastic leukemia (T-ALL) cells16 have been shown to express CD3 but not the Ti determinant detected by monoclonal antibody (MoAb) WT31, which reacts with a nonpolymorphic ...
The first intron of LARGE2 contained a CTTTGATC motif essential for Wnt-driven LARGE2 expression, showed occupation by the Wnt transcription factor TCF7L2, and Wnt activation triggered LARGE2-dependent α-DG O-glycosylation and laminin-adhesion in CRC cells. Colonic crypts and organoids ...
Flow cytometry improves sensitivity for the detection of malignant cells in patients with negative cytology [40,41,42]. However, improved detection of disease in CSF specimen is still needed. The use of circulating deoxyribonucleic acid (ctDNA) has gained traction in recent years. There may be ...
Reduced IL-2 response from peripheral blood mononuclear cells exposed to bacteria at 6 months of age is associated with elevated total-IgE and allergic rhinitis during the first 7 years of life. eBioMedicine 43, 587–593 (2019). Article PubMed PubMed Central Google Scholar de Leeuw, C., ...
Megakaryocytes (MK) generate platelets. Recently, we and others, have reported MK also regulate hematopoietic stem cells (HSC). Here we show high ploidy large cytoplasmic megakaryocytes (LCM) are critical negative regulators of HSC and critical for plate
This vector was tested on a population of EcoR I partial-digest fragments prepared from the DNA of circulating human leukocytes. The uncleaved source DNA had an average size of over 103 kb, while the partial-digest fragments, which were not size-fractionated, were predominantly in the size ...