giant cell tumorpolymethylmethacrylateFoot and ankle surgeons are occasionally confronted with having to fill large defects following excision of osseous lesions. This can prove to be quite challenging to the surgeon in regards to the requirement of large amounts of autogenous, allographic, or ...
However, whether stem cell-derived lEVs are effective for tendinopathy and the underlying mechanism remains unknown. In this study, we investigated the therapeutic effect of lEVs secreted from induced pluripotent stem cell-derived MSCs (iMSC-lEVs) in tendinopathy (both in a rat tendinopathy model ...
We reported two cases of large skin defect of the foot which were treated using a conservative approach, the film-dressing therapy. The therapy was simple, and consisted of washing and dressing the wound with a film. Wound healing was achieved in few months without any sensory disturbance. ...
The predominance of the GRTR pattern among telomere repeat-positive loose ends, in combination with the tumor specificity and forward strand bias, suggested that somatic neotelomeres are frequent in cancer. To better assess sequences fused to GRTR+ loose ends, we profiled three cancer cell lines...
et al. Characterization of diabetic and non-diabetic foot ulcers using single-cell RNA-sequencing. Micromachines (Basel) https://doi.org/10.3390/mi11090815 (2020). Diaz-Papkovich, A., Anderson-Trocme, L., Ben-Eghan, C. & Gravel, S. UMAP reveals cryptic population structure and phenotype ...
A clinically feasible circulating tumor cell sorting system for monitoring the progression of advanced hepatocellular carcinoma Background:Hematogenous metastasis is essential for the progression of advanced hepatocellular carcinoma (HCC) and can occur even after patients receive mu... XY Huang,F Li,TT ...
The germline 7q22.1-q36.1 cnLOH was maintained in the tumor tissue. However, a large percentage of this region also exhibited a gain in mosaicism in approximately 50% of cells (Fig. 1). Specifically, a region close to 15 Mb (7q32.1-q34) presented two copy gains in mosaicism. ...
High Ki-67 expression in diffuse large B-cell lymphoma patients with non-germinal center subtype indicates limited survival benefit from R-CHOP therapy 热度: simultaneous drug targeting of the promoter myc g-quadruplex and bcl2 i-motif in diffuse large b-cell lymphoma delays tumor growth.[2017]...
Automatically manipulating CF40s requires a special “Nunc™ Automatic Cell Factory™ Manipulator System” (Thermo Scientific). Both items together cost six times more than a single Quantum (see Cost Analysis supplement), occupy a much larger footprint and require a large clean/nonclassified (...
Bispecific T cell engagers (BiTEs, Figs.1,2) are a new class of immunotherapy, which enhances the patients’ immune cells to attack tumors by retargeting T cells to tumor cells. Blinatumomab, a CD19/CD3 BiTE, has demonstrated impressive efficacy against B cell acute lymphoblastic leukemia (ALL...