Ductal breast cancerExcess mortality rate ratioLobular breast cancerRelative survival rateBackground Invasive lobular carcinoma (ILC) comprises 8–15 % of all invasive breast cancers and large population-based studies with >10 years of follow-up are rare. Whether ILC has a long-time prognosis ...
Most of these studies were conducted with breast cancers, soft-tissue tumors, lung cancer, prostate cancer, uterine cervix carcinoma, brain tumors, and large-intestine carcinoma. In most of the tumors, prognostic importance of Ki-67 antigen expression was unequivocally confirmed (Brown and Gatter, ...
0.67; 95% confidence interval, 0.514-0.869;P= .0027) was consistent with recent findings fromSOFT (Suppression of Ovarian Function Trial),which also showed a clear survival benefit in breast cancer events with the addition of ovarian function suppression...
Five-year survival rate for patients with all cancers combined, in China, is only 30.9%, which is much lower than those in developed countries. The three main reasons for the low cancer curative rates in China include differences in the spectrum of cancer types, in early detection rates, and...
In many solid tumors and lymphohematopoietic neoplasms, TIM3/Galectin-9 pathway is closely related to CD8+TILs exhaustion, tumor immune evasion, and poor prognosis, such as breast cancer [26], glioma [27], and acute myeloid leukemia [28]. Besides, our study confirmed the positive correlation ...
<sec> Objective: Epigenetic abnormalities have a critical role in breast cancer by regulating gene expression; however, the intricate interrelationships and key roles of approximately 400 epigenetic regulators in
27. PIK3CA-BIRC5 was another reassuring pair as depletion of survivin (BIRC5) has been shown to have a pro-apoptotic effect in breast cancer cells with PIK3CA mutations35,36. In addition to established pairs, SLIdR also predicted several potential SL pairs, such as KRAS-TRPM7 and TP53-...
Pancreatic ductal adenocarcinoma (PDAC), the most deadly solid malignancy, is typically detected late and at an inoperable stage. Early or incidental detection is associated with prolonged survival, but screening asymptomatic individuals for PDAC using a
Breast cancer is the most common cancer amongst Australian women and the second most common cause of cancer-related deaths.1 The life-time risk is considered to be as high as 1 in 91 and, as it is a non preventable disease, early detection is important to increasing survival rates. Woman...
Given the low rate of breast cancer death (3.3% at 20 years) among women in the study — who underwent a variety of treatments for their DCIS — the editorialists believe radiologists and surgeons need to, at the very least, slow down. ...