Langerhans-cell histiocytosisneonatal prematurityBackground Langerhans cell histiocytosis (LCH) is a rare disorder in which Langerhans cells (LC) accumulate in the skin or other organs and cause tumor formation or organ damage. Cutaneous lesions can vary widely and do not predict extent of systemic ...
Langerhans' cell histiocytosis is an uncommon disorder of childhood with a wide clinical spectrum. Although liver involvement is common in the disseminated form, presentation with hepatic disfunction is unusual. We describe an 18-month-old girl who presented with intrahepatic cholestasis. The patient ...
Langerhans cell histiocytosis (LCH) is a poorly understood proliferative disease, with different patterns of clinical presentation. Currently it is classified according to the number and type of system involved and the degree of organ dysfunction. The aetiology of the disease remains uncertain, and in...
Langerhans Cell Histiocytosis Presented as Generalized Vesiculo-Pustules in a Neonate-A Case Report一位女婴自出生後一周起,在头上,脸上,躯干及四肢出现了许多的水及脓,因为疑似疹病毒感染在满月时住院并接受静脉注射acyclovir.虽然单纯疹病毒和水痘带状疹病毒的血清检查与病毒培养的结果都是阴性,但是病灶的直接抗体...
朗格汉斯细胞组织细胞增生症 (Langerhans cell histiocytosis ,LCH)是一种罕见、原因未明、组织细胞增殖性的多系统疾病,旧称组织细胞增生症 X,传统分为三种临床类型,即莱特勒西韦综合征 (Litterer-Siwe 病,简称 L-S 病),汉-薛-柯综合征...
Langerhans cell histiocytosis (LCH) is a relatively rare and unique disease. An incidence of 7.9% in the jaws is reported. We report a case of 9-year-old male child referred to us from dental outpatient department, who presented with a firm swelling in right lower jaw along with bilateral...
Adults generally present after age 40, most of whom have multisystemic disease on presentation. Other myeloproliferative and histiocytic diseases, such as the non-Langerhan cell histiocytosis, may also concur in this population. Pulmonary LCH (PLCH) is a distinct identity that is nearly exclusive ...
朗格汉斯细胞组织细胞增生症(Langerhans cell histiocytosis, LCH)是一组组织细胞增生性疾病,是髓系来源的炎性肿瘤性疾病。其病理特点是CD207(langerin)阳性的未成熟树突状细胞形成肉芽肿样病变,伴局部炎性细胞浸润。 由于LCH来自于造血干细胞,因此可累及全身各个脏器,以皮肤、 骨骼、肺和垂体多见。临床表现异质性强,...
(Langerhans cell histiocytosis,LCH) 是一组以骨髓来源的朗格汉斯细胞(Langerhans cell)异常增生,伴有数量不等的中性粒细胞、嗜酸性粒细胞、淋巴细胞、浆细胞及多核巨细胞浸润,引起组织破坏的疾患。多见于儿童,国外文献示,0-14岁儿童发病率约...
朗格汉斯组织细胞增生症( langerhans cell histiocytosis[,histiəsi'təusis] ,LCH)是由于朗格汉斯细胞异常增生所致的一种未明性质的肿瘤,可累及全身多个系统。(histology[hɪˈstɒlədʒi]组织学 histiocyte[ˈhɪstɪəˌsaɪt]组织细胞),朗格汉斯细胞起源于骨髓而进入表皮,是有吞噬作用...