Langerhans cell histiocytosis (LCH) is a disease with monoclonal proliferation and infiltration of organs by Langerhans cells. LCH is commonly seen in the skeletal system and skin, but it may also involve parenchymal organs. Thyroid involvement in LCH is an unusual presentation. The treatment of ...
朗格汉斯细胞组织细胞增生症 (Langerhans cell histiocytosis ,LCH)是一种罕见、原因未明、组织细胞增殖性的多系统疾病,旧称组织细胞增生症 X,传统分为三种临床类型,即莱特勒西韦综合征 (Litterer-Siwe 病,简称 L-S 病),汉-薛-柯综合征...
摘要:Langerhans组织细胞增生症(LCH)临床表现多样,包括单灶、单系统多灶、单系统肺(吸烟相关)和多系统疾病。本文介绍了成人LCH的临床特征、分类、诊断、治疗和反应评估;建议优选FDG-PET/CT分期和疗效评估;局部治疗可治愈多数单灶疾病;单系统肺LCH...
[3].Anjali Saqi, Adriana P. Kuker, Susana A. Ebner,et al.Langerhans Cell Histiocytosis: Diagnosis on Thyroid Aspirate and Review of the Literature,Head Neck Pathol. 2015 Dec; 9(4): 496–502. [4].Ji Hae Nahm, Gun Yoon, Sung-Im Do,et al.Squash smear cytology of Langerhans cell hi...
Langerhans cell histiocytosis is a rare group of disorders without a well-understood etiology. Known formerly as histiocytosis X, the disease has a wide spectrum of clinical presentations, including eosinophilic granuloma (solitary bone lesion), diabetes insipidus, and exophthalmos. It is also known by...
Langerhans cell histiocytosis (LCH) refers to a collection of syndromes, characterized by infiltration of various tissues by Langerhans cells. In 1941, Farber suggested that eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schüller-Christian dise
Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work-up, and treatment for patients till the age of 18 years Pediatr Blood Cancer, 60 (2) (2013), pp. 175-184 CrossrefView in ScopusGoogle Scholar 28 SC Kaste, C Rodriguez-Galindo, ME McCarville, BL Shulkin PET-CT ...
Langerhans cell histiocytosis (LCH) is a neoplastic disorder that arises from an expansion of early myeloid cells in the bone marrow compartment, most commonly due to a clonal mutation in the RAS/MAP Kinase signaling pathway. This process results in the dissemination of CD1a and CD207 (Langerin...
Langerhans cell histiocytosis is another disease entity encountered in children, with an often aggressive-looking appearance on cross-sectional imaging, making the differential diagnosis with rhabdomyosarcoma difficult.35,36 Although the etiology and pathogenesis is still not well established, it is supposed...
Langerhans cell histiocytosis: diagnosis, natural history, management, and outcome. Cancer. 1999;85(10):2278–90.Hsueh EC, Nathanson L, Foshag LJ et ... V Toma,T Sata,P Vogt,... - 《Cancer》 被引量: 49发表: 2015年 Langerhans cell histiocytosis: diagnosis, natural history, management, ...