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By applying this finding, it was possible to induce the sensitivity of the cancer cells to anticancer drugs, regardless of different mutational backgrounds, cell types, and anti-cancer drugs. Taken together, we suggest that the fitness trade-off is an underlying principle that determines the ...
Here, we assessed to what extent the mCH signature held true for genes likely to escape XCI in mouse liver tissue from two different genetic backgrounds. In mouse liver, the total fraction of methylated cytosines in a CH context (0.1–0.4%) was highly consistent with the range observed in...
These results strongly supported the hypothesis of a monoclonal origin for CTCL5. Interestingly, in patient pcALCL1, in which CD4+and CD8+T cells were both predominant according to histological analysis, CD8+T cells were defined as malignant T cells with clonal expansion and aberrant CNVs. Thus...
These results strongly supported the hypothesis of a monoclonal origin for CTCL5. Interestingly, in patient pcALCL1, in which CD4+and CD8+T cells were both predominant according to histological analysis, CD8+T cells were defined as malignant T cells with clonal expansion and aberrant CNVs. Thus...
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For example, by using bilingual signs, the sign creators aim to ensure the element of diversity in the social sustainability [36,57]. In doing so, these signs involve people from other linguistic backgrounds, values, and viewpoints, which shows that their roles, importance, and participation ...