Reviews (1,827) Drug images Latest FDA alerts (6) Side effects Dosage information During pregnancy Support group Drug class: triazine anticonvulsants Breastfeeding En español Patient resources Lamotrigine drug information Lamotrigine Chewable Dispersible Tablets Lamotrigine Extended-Release Tablets Lamotrigine...
Cases of life-threatening serious rashes, includingStevens-Johnson syndromeandtoxic epidermal necrolysis, or rash-related death have been caused by lamotrigine. The rate of serious rash is greater in pediatric patients than in adults. Additional factors that may increase the risk of rash include: (...
LAMICTAL® can cause serious rashes requiring hospitalization and discontinuation of treatment. The incidence of these rashes, which have included Stevens-Johnson syndrome, is approximately 0.8% (8 per 1,000) in pediatric patients (aged 2 to 16 years) receiving LAMICTAL as adjunctive therapy for e...
pediatric patientsepilepsyThe antiepileptic drug lamotrigine has been assessed in various seizure types and epilepsy syndromes in children and is indicated in the USA and other countries for adjunctive treatment of epilepsy in patients as young as 2 years. This paper reviews data on the ...
This paper reviews the tolerability and safety of ... CL Bowden,GM Asnis,LD Ginsberg,... - 《Drug Safety》 被引量: 159发表: 2004年 Randomized double-blind study comparing the efficacy and safety of lamotrigine and amitriptyline in painful diabetic neuropathy. Aims To compare the efficacy and...
This paper briefly reviews and comments on the development of lamotrigine as a treatment for bipolar disorder. The events described include astute clinical... RH Weisler,JR Calabrese,CL Bowden,... - 《Journal of Afferctive Disorders》 被引量: 317发表: 2008年 Lamotrigine for the treatment of ...
In patients weighing <30 kg, may need to increase maintenance dosage by as much as 50% based on clinical response, regardless of age or concomitant anticonvulsant(s).Table 1: Recommended Pediatric Dosages of Immediate-release Lamotrigine When Added to Anticonvulsant Regimens Containing Valproate1 ...
Lamotrigine(LTG),a new antiepileptic drug,is widely used for the treatment of epilepsy.This paper reviews its classical pharmacokinetics and population pharmacokinetics(PPK),summarizes the effect of polymorphisms and other drugs combination on the pharmacokinetics,as well as clarifies its pharmacokinetics in...
This paper briefly reviews and comments on the development of lamotrigine as a treatment for bipolar disorder. The events described include astute clinical... RH Weisler,JR Calabrese,CL Bowden,... - 《Journal of Afferctive Disorders》 被引量: 316发表: 2008年 Interleaved transcranial magnetic stim...
patients with mild liver impairment. Initial, escalation, and maintenance doses should generally be reduced by approximately 25% in patients with moderate and severe liver impairment without ascites and 50% in patients with severe liver impairment with as cites. Escalation and maintenance doses may ...