Lamotrigine, also known by the brand name Lamictal®, is a second-generation antiepileptic drug (AED) manufactured by GlaxoSmithKline in the UK and USA. Lamotrigine is a new mazine, glutamate inhibitor anticonvulsant that significantly reduces the incidence of refractory partial seizures. The drug ...
Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug. It is thought to work by restoring the balance of cer...
Well known as a Parkinson's disease model, the MPTP animal model also provides a potential paradigm of the energy deficiencies found in childhood. In these conditions, anticonvulsants may provide neuroprotection by limiting cellular energy consumption. We tested valproate, topiramate and lamotrigine in...
Lamotrigine Related Compound C (USP) -Introduction 5-Desamino 5-Oxo-2,5-dihydro Lamotrigine is a drug, also known as a metabolite of 5-amino compounds. It is one of the metabolites of Lamotrigine. The following is a description of its nature, use, formulation and safety information: ...
Discontinuation of lamotrigine at the first sign of a rash, unless the rash is known not to be drug-related. Multi-organ failure has been reported rarely with lamotrigine, usually in association with other serious medical events such as status epilepticus, sepsis, or hantavirus infection. Other...
Lamotrigine is as effective as carbamazepine for the treatment of epilepsy among elderly patients
Twitter Google Share on Facebook lamotrigine Medical Acronyms Wikipedia la·mo·tri·gine (lə-mō′trĭ-jēn′) n. An anticonvulsant drug, C9H7Cl2N5, used also as a mood stabilizer to treat bipolar disorder. [Perhaps (ch)l(oro)- +am(in)o+-trigine(alteration oftriazine).] ...
Lamotrigine also acts as a mood stabilizer. It is approved for the maintenance treatment of bipolar type I. Chemically unrelated to other anticonvulsants (due to Lamotrigine being a Phenyltriazine), lamotrigine has relatively few side-effects and does not require blood monitoring in monotherapy. The...
It is also appropriate for the treatment of Lennox–Gastaut syndrome.[12] It is one of a small number of FDA-approved therapies for this severe form of epilepsy. Lamotrigine reduces the frequency of LGS seizures, and is one of two medications known to decrease the severity of drop attacks....
Multiorgan hypersensitivity (also known as drug reaction with eosinophilia and systemic symptoms [DRESS]) reported; can be fatal or life-threatening. Clinical presentation is variable but typically includes fever, rash, and/or lymphadenopathy with other organ system involvement (e.g., eosinophilia, ...