Terbinafine (Lamisil) 250mg tablets is well absorbed, but bioavailability is decreased to about 40% because of first-pass metabolism in the liver. Proteins bind more than 99% of the drug in plasma. Drug accumulates in skin, nails, and fat. The initial half-life is about 12 hours but exte...
说明书(LAMISIL)01 permanent. Discontinue Lamisil Tablets if smell disturbance occurs. (5.3)Severe neutropenia has been reported. If the neutrophil count is < 1,000 xx/2012 FULL PRESCRIBING INFORMATION: CONTENTS* 1 INDICATIONS AND USAGE 2 DOSAGE AND ADMINISTRATION 3 DOSAGE FORMS AND STRENGTHS ...
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Objective: To determine the cost effectiveness of terbinafine (Lamisil庐)1 tablets compared with fluconazole (Diflucan庐 ) capsules in the treatment of patients with toenail onychomycosis. Methods: Data from a randomised, double-blind, double-dummy, multicentre study were used as the basis for this...
Objective: To determine the cost effectiveness of terbinafine (Lamisil庐)1 tablets compared with fluconazole (Diflucan庐 ) capsules in the treatment of patients with toenail onychomycosis. Methods: Data fro... Heini,Salo,Markku,... - 《Pharmacoeconomics》 被引量: 18发表: 2002年 Cost Effectiveness...
pass metabolism is approximately 40%. Peak plasma concentrations of 1 μg/mL appear within 2 hours after a single 250 mg dose; the AUC is approximately 4.56 μg&bu;ll;h/mL. An increase in the AUC of terbinafine of less than 20% is observed when Lamisil Tablets are administered with ...
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In general, side effects have been mild to moderate and transient; however, this drug has been associated with serious life-threatening events such as hepatic failure,anaphylaxis, and severe neutropenia. Unless otherwise specified, the listed side effects were reported with the tablets.[Ref] ...
Objective: To determine the cost effectiveness of terbinafine (Lamisil庐)1 tablets compared with fluconazole (Diflucan庐 ) capsules in the treatment of pat... H Salo,M Pekurinen - 《Pharmacoeconomics》 被引量: 18发表: 2002年 The Use of Oral Terbinafine (Lamisil®) in Children In an ongoing...