Multilamellar bodies (human lung)SurfactantUltrastructureNormal tissues from human lungs were dehydrated through Epon 812 resin to retain many of the lipids and carbohydrates in thin section. The three-dimensional structure of the multilamellar body was determined. The paired layer of phospholipid heads...
Lunglamellar body amphiphilictopography: a morphological evaluation using the continuum theory of liquid crystals. Anat Rec 1988; 221:520- 32.J.A. Zasadzinski, C. Stratton, R. Rudolph, Lung lamellar body amphiphilic topography: a morphological evaluation using the continuum theor...
Phosphatidyl choline transferase (PCT), very possibly the rate-limiting enzyme in the lecithin biosynthetic pathway, has been described in fetal lung; however, the distinction has not been made between PCT activity in lamellar bodies and that in microsomes, a known site of lecithin biosynthesis. ...
Values between 19×10 3/μL and 40×10 3/μL were the best to predict an intermediate risk of RDS. Lamellar body count is a good screening test for predicting the degree of neonatal lung maturity. 展开 关键词: Lamellar body count Neonatal lung maturity High-risk pregnancy ...
Am J Physiol Lung Cell Mol Physiol. 2007;293(6):1395–405. 18. Matsuzaki Y, Besnard V, Clark JC, Xu Y, Wert SE, Ikegami M, Whitsett JA. STAT3 regulates ABCA3 expression and influ- ences lamellar body formation in alveolar type II cells. Am J Respir Cell Mol Biol. 2008;38(5):...
Choline kinase (CK) activity was assayed in LB rich cell fractions from pooled lung of 6 DBcAMP treated and 6 control rats sacrificed at 15 min. There was a 5-fold increase in CK activity in the DBcAMP treated rats. These findings suggest that intracellular synthesis and extrusion of LB ...
Fig. 5: Outer membrane dome protein (OMDP) observed on the limiting membrane of LB precursors in A549-ABCA3-eGFP and HSAEpC primary lung cells. Full size image Primary lung cells show LB organelles with “T”-junctions and OMDPs Discussion ...
The phospholipid:protein ratio of each of the above fractions was determined as well as that of surfactant lipoprotein isolated from rat lung. Lamellar body phospholipid:protein ratio was highest, 3.7 μmol of lipid phosphorus/mg of lung protein. The phospholipid composition of the lamellar body ...
Article: Isolation, characterization and phospholipid composition of lamellar bodies and subcellular fractions from dog lung
Background: The lamellar body count (LBC) plays a crucial role in fetal lung maturity testing. Lamellar bodies are often counted in the platelet channel of routine hematology analyzers, resulting in a rapid and inexpensive assay for fetal lung maturity.