The results are promising and favor the LAMA/LABA inhalers, especially in the longer duration trials. Furthermore, there is a clearer picture emerging as to the subgroup of COPD patients who may be able to successfully switch from their current ICS/LABA therapy to these new...
The results are promising and favor the LAMA/LABA inhalers, especially in the longer duration trials. Furthermore, there is a clearer picture emerging as to the subgroup of COPD patients who may be able to successfully switch from their current ICS/LABA therapy to these new LAMA/LABA inhaler...
The search terms were "COPD" AND inhaled drugs ("LAMA" AND "LABA") AND randomized controlled design, which included controlled vocabulary and free text. The LAMAs included aclidinium, glycopyrrolate, tiotropium with a dry powder inhaler or soft mist inhaler, and ume- clidinium. The LABAs ...
It is unclear whether adding a LAMA to ICS/LABA therapy has an impact on adherence to treatment, despite the good safety profile. When adding a LAMA to maintenance therapy, it is likely that combining the multiple drugs in one single inhaler device could enhance adherence, but little real-wor...
Inhaled bronchodilators including long-acting beta-agonist (LABA) and long-acting muscarinic antagonist (LAMA) play a central role in the treatment of stable chronic obstructive pulmonary disease (COPD). However, it is still unclear whether LABA or LAMA should be used for the initial treatment. ...
GFF MDI (Bevespi Aerosphere®) is a fixed-dose combination (FDC) of GP (14.4 μg) and the LABA formoterol fumarate dihydrate (FF; 10 μg), delivered by a metered dose inhaler (MDI) using innovative co-suspension delivery technology [[17], [18], [19]]. GFF MDI is the first...
InhalersLABALAMAPharmacotherapyInhaled fixed-dose combinations (FDCs) of a long-acting 尾-agonist (LABA) and a long-acting muscarinic antagonist (LAMA) have become the cornerstone for the maintenance treatment of symptomatic COPD patients. In this regard, global COPD treatment guidelines have ...
InhalersLABALAMAPharmacotherapyInhaled fixed-dose combinations (FDCs) of a long-acting β-agonist (LABA) and a long-acting muscarinic antagonist (LAMA) have become the cornerstone for the maintenance treatment of symptomatic COPD...doi:10.1007/s41030-019-0090-1D’Urzo, Anthony...