type 1diabetes mellitusMetformin is widely prescribed for patients with type 2 diabetes mellitus (DM). Its use for patients with type 1 has been considered a contraindication because of possible adverse effects such as lactic acidosis. However, metformin has been recently used with insulin therapy ...
All patients presented with metabolic abnormalities, including hypoglycemia, and lactic acidosis. 所有这些病人都表现出代谢异常,包括低血糖血症和乳酸性酸中毒。 权威例句 Lactic acidosis. Lactic acidosis LACTIC ACIDOSIS Lactic acidosis in critical illness ...
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Lactic acidosis is a rare but severe complication in patients with type 2 diabetes treated with metformin. Patients with lactic acidosis show commonly signs of shock, tissue hypoxia, acute hepatic or renal failure and the link between metformin therapy and lactic acidosis may be coincidental, associa...
Type B: B1: Underlying diseases (sometimes causing type A) B2: Medication or intoxication B3:Inborn error of metabolism Lactic acidosis is an underlying process of rigor mortis. Tissue in the muscles of the deceased resort to anaerobic metabolism in the absence of oxygen and significant amounts ...
Metformin and lactic acidosis Author information: (1)Geriatric Research, Education and Clinical Center, Veterans Affairs Medical Center, University of Florida, College of Medicine, Gain... JP Monson 被引量: 4发表: 1993年 METFORMIN AND LACTIC ACIDOSIS IN PATIENTS WITH TYPE 2 DIABETES \\u2013 ...
Langerhans cell histiocytosis (LCH) is a rare disorder, characterised by a monoclonal proliferation of aberrant histiocytes that accumulate in and infiltrate into different organs. When the hypothalamic-pituitary axis is involved, centra... ADH Brys,S Vermeersch,R Forsyth,... - 《Netherlands Journal...
However, incorporation of lactate carbon and enhanced respiration was maintained in the presence of uprosertib and lactic acid. Inhibiting lactate transport or oxidative phosphorylation was sufficient to potentiate apoptosis in the presence of uprosertib. Conclusions Lactic acidosis confers resistance to u...
Aim: We suspect that the life-threatening complication of metformin-associated lactic acidosis, solely due to drug accumulation following renal impairment, occurs more frequently than that previously reported and is not necessarily associated with other predisposing factors for lactic acidosis.关键词:co...
Lactic acid is also used as a food preservative. Therapeutically, lactic acid is used in injections, in the form of lactate, as a source of bicarbonate for the treatment of metabolic acidosis; as a spermicidal agent; in pessaries for the treatment of leukorrhea; in infant feeds; and in to...