ERRγlactic acidLRPGC1nuclear translocationTFAMLactic acid (LA) is a byproduct of glycolysis resulting from intense exercise or a metabolic defect in aerobic processes. LA metabolism is essential to prevent lactic acidosis, but the mechanism through which LA regulates its own metabolism is largely ...
3 Treg cells are resistant to lactic acid and use PEPCK-mediated metabolic pathways to support their proliferation. a, Proliferation of CD8+, Tconv and Treg CTV-labelled cells activated in media comprising lactic acid for three days. **P = 0.0058. b, Production of IFNγ by CD8+ and Tconv...
(Lo, Zheng, Hon, et al., 2015). Further improvement of lactic acid production inC. thermocellumby engineering of its metabolic pathways is therefore necessary. Previous studies have suggested that lactic acid production in this strain is likely regulated at multiple levels, namely by: (i) ...
Together, these results indicated that lactic acid was produced in SST cells through the glyco- lytic pathway and may be released via MCT4. However, the tissue localization of MCT2/4 as well as the metabolic pathways that give rise to L-lactic acid should be identified in future studies. ...
Lactic acid can synthesize high value-added chemicals such as poly lactic acid. In order to further minimize the cost of lactic acid production, some effective strategies (e.g., effective mutagenesis and metabolic engineering) have been applied to increase productive capacity of lactic acid bacteria...
Metabolic pathway engineering of cyanobacteria for the production of industrially important chemicals from atmospheric CO2 has generated interest recently... AK Sasaki - 《Bioscience Biotechnology & Biochemistry》 被引量: 0发表: 2013年 Utilization of Lactic Acid Bacterial Genes in Synechocystis sp PCC 680...
Meanwhile, UPLC-MS/MS results suggested that BCT resulted in an augmentation of hypotaurine metabolism, arachidonic acid metabolism, glycolysis/gluconeogenesis, tryptophan metabolism, citrate cycle activity in EC109. The metabolic changes resulted in decreasing in glucose and pyruvate levels but increase ...
Herein, we have summarized the classification of LAB strains, their metabolic pathways for biosynthesis of lactic acid, ethanol, acetic acid and demonstrated their application in various food industries for making fermented milk (yoghurt), cheese, beverages, bread, and animal foods. The wide spectrum...
You produce citric acid, like lactic acid, during cellular metabolism.Unlike lactic acid production, however, citric acid production occurs only when your cells have plenty of oxygen available to them. In fact, the formation of citric acid is the first step of the important metabolic pathway call...
et al. Quantitative metabolic flux analysis reveals an unconventional pathway of fatty acid synthesis in cancer cells deficient for the mitochondrial citrate transport protein. Metab. Eng. 2, 2 (2016). Scientific Reports | (2020) 10:21967 | https://doi.org/10.1038/s41598-020-78955-2 11 Vol...