Lactic acid in shock and liver failure. In: Motet PR, Weber J, eds. Lactate: physiologic, methodologic and pathologic approach. New York: Springer-Verlag New York, 1980:153-62.Perret C, Enrico JF. Lactic acid in shock and liver failure. In: Lactate: Physiologic, Methodologic and Pathologic...
Chronically elevated blood lactic acid, pyruvic acid and increased L:P ratios have been found in a twenty-eight year old woman with episodic acidosis. The patient has no other associated disease. Alcohol ingestion increases the hyperlact... KE Sussman,A Alfrey,WM Kirsch,... - 《American Journ...
In patients at risk for lactic acidosis, such as those with anaerobic metabolism (ie, sepsis, hypoxia), impaired metformin clearance (significant renal impairment), or impaired lactic acid clearance (liver failure), metformin should be avoided.72 Dose reduction is recommended if the estimated glomeru...
The point when lactic acid starts to build up is called the "lactate threshold." Medical conditions.Some medical conditions can also bring on lactic acidosis, including: Lung disorders Circulatory problems Blood disorders Cancer Seizures Liver failure Vitamin B deficiency Sepsis (a whole-body ...
it breaks down glucose to use as energy instead. This process creates lactic acid in the blood. Normally, the kidneys and liver filter out excess lactic acid and turn it back into glucose, which can be used as energy in the future. Lactic acid also spurs your immune system to repair and...
general control of amino-acid synthesis 5 GLUT: glucose transporter GPR81: G-protein coupled receptor 81 HATs: histone acetyltransferases HDAC1-3: histone deacetylase 1–3 HF: heart failure HIF: hypoxia-induced factor HK: hexokinase HSCs:
Lactic acid is produced by various cells in the body, including muscle cells, red blood cells and neurons. In an average adult, around 1,500 mM of lactic acid enters circulation every day (Sun et al, 2017). It’s mostly eliminated by the liver by incorporation into gluconeogenesis (via ...
Lactic acid formation in liver. Estimation of lactic acid in the copperlime filtrates of liver tissue was found unreliable; an ether extraction method gave good; recoveries of added lacti... PA Bott,DW Wilson - 《Journal of Biological Chemistry》 被引量: 5发表: 1935年 Enzymatic Studies on ...
Hemodialysis could adjust acid-base metabolic disturbances, elevate metabolism, and release metformin. Hemodialysis can be discontinued when the serum lactate level is under 3 mmol/L and the pH >7.35 [10]. Conclusions MALA is a rare but life-threatening complication of treatment with metformin. It...
(APTT),serum calcium (Ca2+),pH values,serum lactic acid (Lac),bicarbonate ion (HCO3-),base excess (BE),sodium ion (iNa+) and calcium ion (iCa2+) before and after CRRT were compared between the two groups.Comparison of filter service life and coagulation incidence between the two groups...