Lactate is produced by adipocytes and muscle cells. Objectives: In this study, we investigated the sex differences in lactate production by adipocytes isolated from lean human visceral adipose tissue. Main Methods: The experiments described were done using adipocytes isolated from adipose tissue of ...
Lactate production occurs during anaerobic glycolysis or in proliferatively active cells. L-Lactic Acid occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-Lactic acid is also present in...
Fig. 6.Relationships between B cells and lactate. Upon activation, B cells undergo a complex metabolic reprogramming from proliferation to terminal differentiation into Ig- secreting cells. Lactate production occurs in the early stage of proliferation, and massive Ig secretion is accompanied by alanine...
Quantification of Pan Kla intensity in Iba1+ microglia in (C). All data were presented as the mean ± SEM, n > 100 cells per group, ***p < 0.0001 Full size image H4K12la levels are elevated in microglia after SCI Previous...
In subject area:Neuroscience Lactate dehydrogenase is an enzyme that converts pyruvate to lactate and vice versa, while also converting NADH to NAD. It plays a role in energy production during anaerobic conditions and is associated with muscle breakdown under certain conditions. ...
infiltrating cells in the inflammatory microenvironment are highly glycolytic. several enzymes are involved in glucose glycolysis that leads to the production of lactate, which serves as an important carbon source for cell metabolism and enables the transition between glycolysis, oxphos, and fatty acid ...
Background: This investigation assesses the prognostic value of lactate levels and their clearance in septic shock patients, particularly emphasizing the comparative analysis between COVID-19 and non-COVID-19 patients in the emergency department. This study aims to elucidate the unique prognostic implica...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook Clearance (redirected fromlactate clearance) Dictionary Thesaurus Medical Legal Encyclopedia Clearance The process ofsettlingtransactions. Most exchanges have one or moreclearing houses, which are charged with matchingorder...
The concept of intercellular lactate shuttling was proposed and systematically explained in 19852. The theory suggests that at the beginning of exercise, lactate is rapidly produced and accumulates in muscle cells; then, some of this lactate enters tissues, where it is internalized and oxidized by ...
There is no net production of hydrogen ions in this process, and therefore no production of acid. When cells hydrolyze ATP for energy, protons are released; as lactate is consumed, an Lactate Reference Intervals and Sampling Techniques Plasma lactate concentration intervals as measured by laboratory...