The production of lactate as fuel increases when the demand for oxygen and ATP exceeds the cellular supply, such as during strenuous exercise and infection21,22. Lactate is a classical byproduct of glucose metabolism, and the main lactate production pathway depends on glycolysis (Fig.1). The gl...
SCI is known to cause microvascular damage and inflammation, resulting in an ischemic and hypoxic microenvironment in the metabolically active spinal cord, thereby disrupting the coupling of glycolysis and oxidative phosphorylation [11, 12]. Lactate, produced as a byproduct of glycolytic metabolism under...
(ndufa4l2). ndufa4l2 is a subunit of respiratory complex i that limits the activity of this complex and the generation of mitochondrial ros, which is a byproduct of complex i. the activated hif-1α/ndufa4l2 pathway restricts mitochondrial respiration in dcs by repressing the increase in ...
"With critically ill cats, it can sometimes be difficult to accurately determine a prognosis," said Deborah C. Silverstein, an associate professor in the Department of Clinical Studies at Penn Vet and senior author on the study. "No one is ever going to look at a patient that appears really...
Lactate byproduct containing calcium carbonate or calcium hydroxide, as a neutralizing agent to continue recycling, that is, without waste emissions, but also increase the lactate extraction yields and reduce production costs.CN高大成佟明友黎元生
Comparison of the AUC of the HLMRG signature with those of the other groups. **P < 0.01 Full size image Lactate is traditionally recognized as a byproduct derived from glucose metabolism. More recently, there is growing evidence indicates that role of lactate is a key player in the regu...
Recently, we reported a unique microbiome that is predominated by Clostridium cluster IV, which can efficiently convert lactate into high level of CA as the primary product [18]. In batch fermentation with sufficient lactate addition, the maximum CA titer reached up to 23.4 g/L, with a CA ...
10. The method of claim 1 further comprising: recovering the catalyst; and recycling the catalyst. 11. The method of claim 1 wherein the saccharide is a polysaccharide and further comprising hydrolyzing the polysaccharide. 12. The method of claim 11 wherein the polysaccharide is hydrolyzed by he...
[16,17,18,19]. Lactate is a crucial brain metabolite which is primarily produced in astrocytes [20,21] and muscle tissue during physical exercise [22,23,24] from where it may reach the brain through blood circulation [25,26]. Initially regarded as a mere metabolic byproduct requiring ...
Fermentation is a metabolic process that occurs in certain microorganisms, such as yeast or bacteria, without oxygen. It involves the conversion of sugars or other organic compounds into simpler substances, such as alcohol, carbon dioxide, or organic acids. Answer and...