Based on the favourable COX-2 inhibition profile, compound N-(4-fluorobenzyl)-4-(5-p- 5to. l2y0l-135-trifluoromethylpyrazol- 1-yl)benzenesulfonamide 31 (IC50 = 0.36 µM, SI > 277) was selectTehdefdoirsc18oFvlearbyeollfinagflaunodrePscEeTntimpraogbien,gCsetluedcoiexsi.bR-NadBiDol[i5...