Here we propose a new method to automatically segment and label different compartments of the ventricles in NPH patients from MRIs. While this task has been achieved in healthy subjects, the ventricles in NPH are both enlarged and deformed, causing current algorithms to fail. Here we combine a ...
†ΦΔ values for DBF are given in the literature32. Extended Data Fig. 2 Covalent modification of AMPAR with MBF and subsequent light-triggered proximity labeling in the live mouse brain. (a) Western blot of brain tissue isolated from mice injected to the lateral ventricles with 1 and ...
Anatomical atlases in standard coordinates are necessary for the interpretation and integration of research findings in a common spatial context. However, the two most-used mouse brain atlases, the Franklin-Paxinos (FP) and the common coordinate framewor
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For quite some time, it has been known that CSF movement results from the formation of new CSF and motion of cilia on the surface of the choroid plexus and ependyma lining the ventricles. In the last three decades, MRI cardiac-gated PC cine techniques have been widely applied to study CSF...
HIE-related lesions in brain MRI are often diffuse (i.e., multi-focal), and small (over half the patients in our data having lesions occupying<1% of thebrain volume(including ventricles)). Segmentation for HIE MRI data is remarkably different from, and arguably more challenging than, other ...
The CSF water exchange was 1153 ± 270 mL/100 mL/min with T 1 ‐PALAN in the third and lateral ventricles, which was higher than 891 ± 60 mL/100 mL/min obtained by ADC‐PALAN. T 1 ‐PALAN ?S values for the rostral and caudal ventricles are 0.015 ± 0.013 and 0.034 ± 0.01 ( ...
Cerebrospinal fluid (CSF) is a clear, colorless fluid that serves vital functions in protecting and nourishing the brain and spinal cord [1]. It is produced in specialized structures called the choroid plexus located in the brain’s ventricles. From there, it follows a specific pathway, flowing...